Born in Arucas, Las Palmas, Canary Islands, Manuel Pablo was only 22 when he joined Deportivo de La Coruña from hometown's UD Las Palmasin the summer of 1998, being signed together with Argentine Turu Flores. He made his La Liga debut on 15 November 1998 in a 2–2 home draw against Deportivo Alavés, but faced serious competition from Armando in his first season, appearing in just 14 league matches. Manuel Pablo played 74 games from 1999 to 2001, and was a vital part of Depor's defense as the Galicians were crowned national champions in 2000for the first time in their history. His performances earned him a debut with the Spanish national team on 16 August2000, in a 1–4 away friendly defeat to Germany. In his fourth season at A Coruña, disaster struck: on 30 September 2001, Manuel Pablo sustained an horrific tibia injury during the Galician derby against Celta de Vigo, in a televised match, after an unlucky tackle by Everton Giovanella. Eventually, he missed the rest of the campaign. One year later, Manuel Pablo returned, playing the full 90 minutes against CD Corralejo in a Copa del Reytie. On 6 October 2002 he was handed his league return by coach Javier Irureta, coming out as a late substitute in the 0–2 home loss to Racing de Santander. In 2003–04's closing stages Manuel Pablo proved he was fully recovered, as displayed in an excellent individual display on 7 April 2004 in a 4–0 second leg quarterfinal crushing of A.C. Milan in the UEFA Champions League. From the 2004–05 season onwards, he was the undisputed right-back at Riazor. In the following two seasons, Manuel Pablo remained first-choice at his position, although he was challenged by younger Laure in 2008–09. In early May 2009, after lengthy negotiations, the 33-year-old renewed his Depor contract in a 2+1 deal. From 2009 to 2015, Manuel Pablo still managed to appear in a combined 126 league games, being relegated twice from the top flight and achieving as many promotions. On 16 June 2015, he extended his link for a further year. On 7 July 2016, after only five competitive appearances during the season, 40-year-old Manuel Pablo retired.
