Main Street Commercial Historic District
- Main Street Commercial District (Dothan, Alabama)
- Main Street Commercial District (Georgetown, Kentucky)
- Main Street Commercial District (Little Rock, Arkansas)
- Main Street Commercial Historic District (Hamlet, North Carolina)
- Main Street Commercial Historic District (Jefferson, Wisconsin)
- Main Street Commercial Historic District (Kalispell, Montana)
- Main Street Commercial Historic District (Platteville, Wisconsin)
- Main Street Commercial Historic District (Reedsburg, Wisconsin)
- Main Street Commercial Historic District (Watertown, Wisconsin)
- Main Street Historic Commercial District (Georgetown, Kentucky)
- Main Street Historic Commercial District (Point Arena, California)
- Main Street Historic District (disambiguation)
- National Register of Historic Places listings in Dane County, Wisconsin
- National Register of Historic Places listings in Grant County, Wisconsin
- National Register of Historic Places listings in Houston County, Alabama
- National Register of Historic Places listings in Jefferson County, Wisconsin
- National Register of Historic Places listings in Little Rock, Arkansas
- National Register of Historic Places listings in Richmond County, North Carolina
- National Register of Historic Places listings in Scott County, Kentucky
- Stoughton Main Street Commercial Historic District