Murakami made her senior debut at the 2012 National Championships where she placed eleventh in the all-around. She was not named to the 2012 Olympic team. Murakami competed at the 2012 Stuttgart World Cup where Japan finished second to Russia. Murakami competed at the 2013 City of Jesolo Trophy where she won bronze with the Japanese team and placed 22nd in the all-around. She finished third in the all-around at both the National Championships and the NHK Cup. She finished fourth on the floor exercise at the 2013 World Championships.
2014-2015
Murakami competed at the 2014 Pacific Rim Gymnastics Championships placing fourth with the team, sixth on floor, seventh on bars and beam, and ninth in the all-around. She placed sixth in the all-around at the National Championships and fourth at the NHK Cup. At the All Japan Championships, she won gold on floor and silver on vault. She was then selected to compete at the 2014 World Championships along with Asuka Teramoto, Yu Minobe, Natsumi Sasada, Wakana Inoue, and Azumi Ishikura, and they finished in eighth place. After the World Championships Murakami finished the season by placed fifth in the all-around at the Glasgow World and winning vault and floor at the Toyota International. At the 2015 National Championships, Murakami struggled on beam and floor and placed tenth in the all-around. She placed eighth in the all-around at the NHK Cup, but at the Event Championships she won bronze on vault and gold on floor. Murakami was initially named an alternate for the World Championships, but an injury led to her joining the team. The Japanese team placed fifth, and she placed sixth in the all-around, the best finish by a Japanese woman in six years.
2016
Murakami competed at the American Cup where she placed sixth in the all-around. She then won the all-around at the National Championships in addition to winning gold on floor and bronze on vault and beam. At the NHK Cup, she finished second in the all-around behind Asuka Teramoto, and she won gold on floor and silver on vault. At the Event National Championships, she won gold on floor exercise and placed fourth on uneven bars. She was then named to represent Japan at the 2016 Summer Olympics along with Asuka Teramoto, Aiko Sugihara, Yuki Uchiyama, and Sae Miyakawa.
Japan competed in the final subdivision of the qualification round, and they qualified seventh into the team final, and individually Murakami qualified ninth into the all-around and eighth on floor exercise. The team then finished fourth in the team final. Murakami placed fourteenth in the all-around final with a score of 56.665. She then placed seventh in the floor exercise final with a score of 14.533.
2017
Murakami won the all-around at the National Championships in addition to winning gold on beam and floor and winning silver on vault. She also won the all-around at the NHK Cup and won gold on beam and floor and bronze on vault and uneven bars. She was then automatically named to the World Championship team along with Aiko Sugihara. She then won silver on floor and placed fifth on vault at the Event National Championships. At the 2017 Artistic Gymnastics World Championships in Montreal, Quebec, Canada, she qualified first into the all-around final, ahead of American gymnast Ragan Smith, but had a fall in the finals, and ended up in 4th place, one-tenth of a point behind the bronze medalist, Russia's Elena Eremina. She redeemed herself in the floor exercise finals, where she placed first ahead of Jade Carey and Claudia Fragapane. She is Japan's first Worldgold medalist on this event, and Japan's second World gold medalist on any women's gymnastics event, after Keiko Tanaka-Ikeda won the gold on the balance beam in 1954. Afterward, she won gold on floor and bronze on vault at the Toyota International.
2018
Murakami finished second at the American Cup behind Morgan Hurd. She then won the all-around at the Tokyo World Cup. Then, she won the all-around at both the National Championships and the NHK Cup. She won gold on balance beam and floor exercise at the Event National Championships. At the 2018 Artistic Gymnastics World Championships in Doha, Qatar the Japanese team finished in sixth place. Individually, she finished second in the all-around final, behind Simone Biles. It is the first women’s all-around silver medal in Japan’s history. She then won the bronze medal in the floor exercise final behind Biles and Morgan Hurd.
2019
Murakami won a bronze medal in the all-around at the American Cup behind Americans Leanne Wong and Grace McCallum. Murakami missed the NHK Cup due to a back injury, but because of this, Murakami was deemed ineligible to make the Japanese team for the World Championships. Murakami's petition was denied.
2020
In February it was announced that Murakami would represent Japan at the Tokyo World Cup taking place on April 4.
