Bernadeau was selected in the seventh round of the 2008 NFL Draft. He was the first Northeast-10 Conference player ever drafted in the NFL. In 2009, he appeared in all 16 games, starting at left guard during the last 7 games, after left tackle Jordan Gross was lost for the season with an injury and Travelle Wharton was forced to move from guard to tackle. His best season with the Panthers came the next year, when he started 12 games. In 2011, he lost his starting position to Wharton, playing in 15 games with one start at left guard.
On March 14, 2012, Bernadeau signed with the Dallas Cowboys as a free agent. After having hip and knee surgery in the offseason, his level of play suffered, even though he started 16 games for the first time in his career. The next year, he had another offseason surgery, this time in his right shoulder. After starting the first game of the 2013 season, the Cowboys signed former Pro BowlerBrian Waters to start in place of Bernadeau and improve the level of play on the offensive line. After Waters was lost for the season with a triceps injury in the eighth game, Bernadeau regained his starter role and went on to play his best football as a Cowboy. Looking to improve the guard position, the team selected Zack Martin in the first round of the 2014 NFL Draft and moved Bernadeu to compete for the left guard position, which eventually went to Ronald Leary. He only started one game in place of an injured Leary and remained as a backup for the rest of the season. In 2015, he was used as a versatile backup that could play any of the interior positions of the offensive line, including center. He started in the second game of the season against the Philadelphia Eagles, replacing an injured Ronald Leary at left guard. He saw limited action until the last game against the Washington Redskins, when he replaced an injured Leary in the third quarter.
On March 11, 2016, Bernadeau signed a two-year contract with the Jacksonville Jaguars. Although he began training camp as the starter at left guard, he was passed on the depth chart by Chris Reed and Patrick Omameh and was relegated to third-string center duties. He was released on September 3.
Personal life
Bernadeau is one of six siblings. Bernadeau enjoys karaoke as he is a world recognized champion in the activity. Competing in Berlin in 2012 and Montreal in 2013 Bernadeau took home gold in both events. He credits his mother for giving him his sweet sounding voice.