List of predecessors of the St. Louis–San Francisco Railway
The following railroad companies became part of the St. Louis–San Francisco Railway system, usually through consolidation.
Early lines in Missouri and Kansas
The Frisco started out as the Southwest Branch of the Pacific Railroad, and was split out in 1866. That same year, Congress incorporated the Atlantic and Pacific Railroad, which would end up extending the line through Springfield and Tulsa to Sapulpa.| Name | Incorporation | Began operations | Succession | Notes |
| St. Louis–San Francisco Railway | 1916 | 1916 | 1980 | - |
| St. Louis and San Francisco Railroad | 1896 | 1896 | 1916 | - |
| St. Louis and San Francisco Railway | 1876 | 1876 | 1896 | - |
| Atlantic and Pacific Railroad | 1866 | 1870 | 1876 ; 1897 1897 | - |
| South Pacific Railroad | 1868 | 1868 | 1870 | - |
| Southwest Pacific Railroad | 1866 | 1866 | 1868 | - |
| Pacific Railroad | 1849 | 1852 | 1866 1876 | - |
| St. Louis, Salem and Arkansas Railway | 1887 | 1887 | 1897 | Cuba to Salem with branches |
| St. Louis, Salem and Little Rock Railroad | 1871 | 1873 | 1887 | - |
| Sligo Furnace Railroad | 1880 | 1881 | 1881 | - |
| Dent and Phelps Railroad | 1877 | 1878 | 1881 | - |
| Crawford County Midland Railroad | 1904 | 1905 | 1905 | Branch of the line to Salem |
| Springfield Connecting Railway | 1886 | 1887 | 1926 | - |
| Springfield and Southern Railway | 1882 | 1883 | 1885 | Springfield to Chadwick |
| Springfield and Northern Railway | 1884 | 1884 | 1885 | Springfield to Bolivar |
| Kansas City, Osceola and Southern Railway | 1891 | 1891 | 1900 | Bolivar to Kansas City |
| Kansas City and Southern Railway | 1880 | 1885 | 1891 | - |
| Kansas City, Memphis and Mobile Railroad | 1871 | N/A | 1880 | - |
| Missouri and Western Railway | 1875 | 1875 | 1879 | Pierce City to Oswego, with a branch to Joplin |
| Pierce City and Kansas Railroad | 1875 | N/A | 1875 | - |
| Oswego and State Line Railroad | 1875 | N/A | 1875 | - |
| Memphis, Carthage and Northwestern Railroad | 1871 | 1872 | 1877 | - |
| State Line, Oswego and Southern Kansas Railway | 1872 | N/A | 1872 | - |
| St. Louis, Wichita and Western Railway | 1879 | 1879 | 1882 | Oswego to Wichita |
| Kansas Midland Railroad | 1900 | 1900 | 1900 | Wichita to Ellsworth |
| Kansas Midland Railway | 1886 | 1888 | 1900 | - |
| Joplin Railway | 1882 | 1882 | 1882 | Girard to Galena via Joplin |
| Joplin and Galena Railway | 1880 | 1881 | 1882 | - |
| Joplin Railroad | 1874 | 1877 | 1882 | - |
| Pittsburg and Columbus Railway | 1886 | 1887 | 1926 | Pittsburg to Weir |
| West Tulsa Belt Railway | 1909 | 1910 | 1922 | - |
St. Louis, Memphis and Southeastern Railroad
Kansas City, Fort Scott and Memphis Railway
Other extensions into Arkansas, Oklahoma, and Texas
Because of a provision of the Texas Constitution, railroad companies operating in that state had to be incorporated in Texas. The Frisco's primary Texas subsidiary was the St. Louis, San Francisco and Texas Railway.| Name | Incorporation | Began operations | Succession | Notes |
| Arkansas and Choctaw Railway | 1895 | 1895 | The St. Louis and San Francisco Railroad Company took control of the owner’s stock January 1, 1904; the property was deeded to the St. Louis and San Francisco Railroad Company on November 30, 1907. | Main line from Hope, Arkansas to Ardmore, Oklahoma |
| St. Louis and Oklahoma City Railroad | 1895 | 1898 | 1899 | Sapulpa to Oklahoma City |
| Oklahoma City Terminal Railroad | 1900 | 1900 | 1901 | - |
| Oklahoma City and Western Railroad | 1899 | 1902 | 1907 | Oklahoma City to state line near Quanah |
| Oklahoma City and Texas Railroad | 1901 | 1903 | 1904 | State line to Quanah |
| Quanah, Acme and Pacific Railway | 1909 | 1910 | 1981 | Quanah to Floydada |
| Acme, Red River and Northern Railway | 1902 | N/A | 1909 | - |
| Motley County Railway | 1913 | 1914 | 1926 | Branch of Quanah, Acme and Pacific to Matador |
| Sapulpa and Oil Field Railroad | 1915 | 1916 | 1917 | Depew to Shamrock |
| St. Louis, Oklahoma and Southern Railway | 1895 | 1900 | 1901 | Sapulpa to state line near Denison |
| St. Louis, San Francisco and Texas Railway | 1900 | 1901 | 1964 | State line to Denison |
| Red River, Texas and Southern Railway | 1901 | 1902 | 1904 | Denison to Dallas and Fort Worth |
| Sulphur Springs Railway | 1902 | 1903 | 1907 | Scullin to Sulphur |
| Arkansas Valley and Western Railway | 1902 | 1904 | 1907 | Tulsa to Avard |
| St. Louis, Arkansas and Texas Railway | 1880 | 1880 | 1882 | Monett to Fort Smith; completed by the Frisco |
| Missouri, Arkansas and Southern Railway | 1880 | N/A | 1881 | - |
| Fort Smith and Van Buren Bridge Company | 1885 | 1886 | 1907 | - |
| Fort Smith and Southern Railway | 1886 | 1887 | 1887 | Fort Smith to the state line near Paris; completed by the Frisco |
| Paris and Great Northern Railroad | 1881 | 1888 | 1928 | State line to Paris |
| Arkansas and Oklahoma Railroad | 1898 | 1898 | 1901 | Rogers to Grove via Bentonville |
| Bentonville Railroad | 1882 | 1883 | 1900 | - |
| Fayetteville and Little Rock Railroad | 1886 | 1887 | 1887 ; 1926 | Fayetteville to Pettigrew |
| Ozark and Cherokee Central Railway | 1901 | 1903 | 1907 | Fayetteville to Okmulgee |
| North Arkansas and Western Railway | 1899 | N/A | 1901 | - |
| Muskogee City Bridge Company | 1901 | 1903 | 1903 | - |
| Shawnee, Oklahoma and Missouri Coal and Railway Company | 1899 | 1903 | 1903 | - |
| Little Rock and Texas Railway | 1887 | 1887 | 1926 | Hackett to Mansfield |
| Kansas City and Southwestern Railroad | 1884 | 1885 | 1897 | Beaumont to state line near Arkansas City |
| Kansas, Oklahoma and Gulf Railway | 1897 | 1899 | 1899 | State line near Arkansas City to Blackwell |
| Blackwell, Enid and Southwestern Railway | 1900 | 1901 | 1907 | Blackwell to state line near Vernon |
| Blackwell, Enid and Texas Railway | 1901 | 1902 | 1904 | State line to Vernon |
| St. Louis, San Francisco and New Orleans Railroad | 1902 | 1902 | 1907 | Hope to Ardmore, with a branch to near Denison |
| Arkansas and Choctaw Railway | 1895 | 1896 | 1902 | - |