List of investigational sexual dysfunction drugs

Atrophic vaginitis

• Estetrol – estrogen receptor agonist
• Lasofoxifene – selective estrogen receptor modulator

  Erectile dysfunction

• HCP-1302 – undefined mechanism of action
• Nitroglycerin gel – nitric oxide donor
• Tadalafil/tamsulosin
• TT-701 – selective androgen receptor modulator

  Female anorgasmia

• Testosterone low-dose intranasal – androgen receptor agonist

  Female sexual dysfunction

• BP-101 – undefined mechanism of action
• Bupropion/trazodone – norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, 5-HT_2A receptor antagonist, α₁-adrenergic receptor antagonist, weak serotonin reuptake inhibitor
• Buspirone/testosterone – 5-HT_1A receptor partial agonist and androgen receptor agonist
• Lasofoxifene – selective estrogen receptor modulator
• PL-6983 – selective MC₄ receptor agonist
• Sildenafil/testosterone – PDE5 inhibitor and androgen receptor agonist
• TGFK09SD – 5-HT_1A receptor agonist

  Premature ejaculation

• Clomipramine/sildenafil – serotonin reuptake inhibitor and PDE5 inhibitor
• DA-8031 – serotonin reuptake inhibitor
• IX-01 – oxytocin receptor antagonist
• OnabotulinumtoxinA – acetylcholine release inhibitor
• Tramadol – μ-opioid receptor agonist, serotonin releasing agent, norepinephrine reuptake inhibitor, and 5-HT_2C receptor antagonist

  Unspecified

• Vilazodone – 5-HT_1A receptor partial agonist and serotonin reuptake inhibitor