List of best-selling Sega Genesis games
This is a list of Sega Genesis/Mega Drive video games that have sold or shipped at least one million copies, sorted in order of copies sold.
List
| Title | Copies sold | Release date |
| Sonic the Hedgehog | 15 million | |
| Sonic the Hedgehog 2 | 6 million | |
| Disney's Aladdin | 4 million | |
| Sonic the Hedgehog 3 and Sonic & Knuckles | 4 million | |
| NBA Jam | at least 1.93 million in the US | |
| Mortal Kombat II | at least 1.78 million in the US | |
| 1.65 million | ||
| Altered Beast | at least 1.4 million in the US | |
| Mortal Kombat 3 | 1.02 million in the US | |
| Jurassic Park | more than 1 million | 1993 |
| Ms. Pac-Man | more than 1 million in the US | 1993 |
| NFL '98 | more than 1 million in the US | 1998 |
| NFL Football '94 | more than 1 million | 1994 |
| Sonic Spinball | more than 1 million | 1993 |
| X-Men | more than 1 million | 1993 |
| Mighty Morphin Power Rangers | 1 million in the US | 1994 |