List of United States senators from South Carolina
ratified the United States Constitution on May 23, 1788. Its Senate seats were declared vacant in July 1861 owing to its secession from the Union. They were again filled from July 1868. The state's current U.S. senators are Republicans Lindsey Graham, serving since 2003, and Tim Scott, serving since 2013.! rowspan=4 | 1
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! rowspan=6 | 27Living former senators
, there is one living former U.S. senator from South Carolina. The most recent senator to die was Fritz Hollings on April 6, 2019, and was also the most recently serving senator to die.
| Senator | Term of office | Date of birth |
| Jim DeMint | 2005–2013 | |
