List of 1999 box office number-one films in the United Kingdom
This is a list of films which have placed number one at the weekend box office in the United Kingdom during 1999.
| # | Weekend End Date | Film | Box Office | Notes |
| 1 | 3 January 1999 | ' | £2,706,800 | |
| 2 | 10 January 1999 | Star Trek: Insurrection | £1,132,823 | |
| 3 | 17 January 1999 | Meet Joe Black | £986,511 | |
| 4 | 24 January 1999 | Practical Magic | £1,001,536 | |
| 5 | 31 January 1999 | Shakespeare in Love | £1,819,385 | |
| 6 | 7 February 1999 | A Bug's Life | £4,204,678 | |
| 7 | 14 February 1999 | A Bug's Life | £4,107,566 | |
| 8 | 21 February 1999 | A Bug's Life | £4,311,358 | |
| 9 | 28 February 1999 | A Bug's Life | £2,220,635 | |
| 10 | 7 March 1999 | A Bug's Life | £1,509,076 | |
| 11 | 14 March 1999 | Patch Adams | £786,778 | |
| 12 | 21 March 1999 | Waking Ned | £911,901 | |
| 13 | 28 March 1999 | The Rugrats Movie | £1,971,685 | |
| 14 | 4 April 1999 | The Rugrats Movie | £1,403,862 | |
| 15 | 11 April 1999 | The Rugrats Movie | £1,326,486 | |
| 16 | 18 April 1999 | The Faculty | £822,777 | |
| 17 | 25 April 1999 | 8MM | £733,535 | |
| 18 | 2 May 1999 | The Waterboy | £887,245 | |
| 19 | 9 May 1999 | I Still Know What You Did Last Summer | £802,498 | |
| 20 | 16 May 1999 | Forces of Nature | £493,897 | |
| 21 | 23 May 1999 | She's All That | £1,200,565 | |
| 22 | 30 May 1999 | Notting Hill | £4,323,678 | |
| 23 | 6 June 1999 | Notting Hill | £3,004,696 | |
| 24 | 13 June 1999 | The Matrix | £3,384,948 | |
| 25 | 20 June 1999 | The Matrix | £2,275,576 | |
| 26 | 27 June 1999 | The Mummy | £3,771,429 | |
| 27 | 4 July 1999 | The Mummy | £2,535,195 | |
| 28 | 11 July 1999 | The Mummy | £1,278,869 | |
| 29 | 18 July 1999 | ' | £9,512,295 | |
| 30 | 25 July 1999 | Star Wars Episode I: The Phantom Menace | £5,104,514 | |
| 31 | 1 August 1999 | ' | £6,005,087 | |
| 32 | 8 August 1999 | Austin Powers: The Spy Who Shagged Me | £3,421,492 | |
| 33 | 15 August 1999 | Wild Wild West | £2,487,176 | |
| 34 | 22 August 1999 | Star Wars Episode I: The Phantom Menace | £1,420,885 | |
| 35 | 29 August 1999 | ' | £1,496,581 | |
| 36 | 5 September 1999 | South Park: Bigger, Longer & Uncut | £813,613 | |
| 37 | 12 September 1999 | Eyes Wide Shut | £1,189,672 | |
| 38 | 19 September 1999 | Eyes Wide Shut | £881,889 | |
| 39 | 26 September 1999 | The Haunting | £1,562,169 | |
| 40 | 3 October 1999 | Big Daddy | £1,360,121 | |
| 41 | 10 October 1999 | American Pie | £2,094,122 | |
| 42 | 17 October 1999 | Deep Blue Sea | £1,946,454 | |
| 43 | 24 October 1999 | Tarzan | £3,055,218 | |
| 44 | 31 October 1999 | The Blair Witch Project | £5,875,318 | |
| 45 | 7 November 1999 | The Blair Witch Project | £2,290,106 | |
| 46 | 14 November 1999 | The Sixth Sense | £4,792,296 | |
| 47 | 21 November 1999 | The Sixth Sense | £3,277,054 | |
| 48 | 28 November 1999 | The World Is Not Enough | £6,273,584 | |
| 49 | 5 December 1999 | The World Is Not Enough | £3,842,119 | |
| 50 | 12 December 1999 | The World Is Not Enough | £2,329,718 | |
| 51 | 19 December 1999 | The World Is Not Enough | £1,389,490 | |
| 52 | 26 December 1999 | The World Is Not Enough | £336,718 | |
| 53 | 2 January 2000 | The World Is Not Enough | £797,142 |