Limulus clotting factor C
Limulus clotting factor overbar C is an enzyme. This enzyme catalyses the following chemical reaction
This enzyme is isolated from the hemocyte granules of the horseshoe crabs Limulus and Tachypleus, where is serves as a LPS endotoxin-sensitive trypsin type serine protease to protect the organism from bacterial infection, initiating a cascade leading to coagulin formation. From the N-terminus to the C-terminus, the domains are:
This enzyme is useful in Limulus amebocyte lysate as the endotoxin-detecting element. It can be produced recombinantly.
