Leprosy in Japan

History

Ancient and medieval ages

• The route of leprosy into Japan has not been settled but the presence of leprosy in Japan at least in the Nara Era and the earliest record of leprosy in Korea at Cheju Island in 1445 suggests that leprosy came from the south.
• In a collection of government documents titled "Ryounogige", written in 833, leprosy was described as the following: "It is caused by a parasite which eats five organs of the body. The eyebrows and eyelashes come off, and the nose is deformed. The disease brings hoarseness and necessitates amputations of the fingers and toes. Do not sleep with the patients, as the disease is transmittable to those nearby."
• *This is the first document in the world that identifies leprosy as transmissible since there had been no such documents in China.
• *Kensuke Mitsuda thought that this was because of the frequent complication of scabies with leprosy since scabies is easily transmitted.
• According to a legend, Empress Komyo washed a leprosy patient in the 8th century.
• In medieval times, people with leprosy were discriminated against and lived separately from the main dwelling areas of the villages. This discrimination was bolstered by religion — one of the sutras of the Nichiren sect stated that "those who do not respect this sutra will get leprosy in the next stage of life."
• During the short period when Catholic priests were allowed to preach Christianity, they built special hospitals where they treated leprosy patients. This came to an end when the Tokugawa Government enacted the death penalty for the crime of being a Catholic.
• Otani Yoshitsugu a famous samurai of the Sengoku era also suffered from leprosy. It was said to be one of the factors that led to his defeat at the battle of Sekigahara in 1600.

  The Meiji Era (1868–1912)

• Japan reopened its doors to foreign countries in 1868, and the power went to the Emperor and the democratic government. Checkpoints between provinces were abolished in 1871, and leprosy patients could also freely travel in the country.
• In the same year, leprosy patients began to line up on the road to Honmyoji, a noted temple in Kumamoto, Kyushu, Japan, for mercy. The first national survey conducted in 1904 indicated that there were 30,359 patients, but because of the methodology, this figure may be vastly underestimated.

  Christian missionaries and Japanese savers

• Japanese people were accustomed to seeing people with leprosy begging for money at temples and shrines or wherever people gathered, but this was a shocking event to Europeans. Upon seeing a miserable 30-year-old woman abandoned near a watermill, Father Testevuide became determined to establish a facility for such people. In 1889, he started the Kohyama Fukusei Hospital. His example was followed by Kate Youngman in Tokyo, Miss Hannah Riddell and Father Corre in Kumamoto.
• In 1875, Dr. Masafumi Goto founded the Kihai Hospital in Tokyo which was specially designed to treat leprosy patients. Dr. Goto and his son, Dr. Masanao Goto, became widely known for their balneotherapy for leprosy patients. At the request of the King of the Hawaiian Kingdom, Dr. Masasao Goto visited Hawaii and introduced their method. Most of the Japanese doctors who established these facilities discontinued their activities after the start of public leprosy sanatoriums.

  1905 epoch-making meeting

"No Leprosy Patients in Prefecture" Movement

• At the start of public sanatoriums, only the wandering patients were hospitalized. However, as time went, people wanted their prefectures to be "purified," and the belief began that there should be no leprosy patients in their prefectures.
• This movement started around 1930 and it naturally worsened leprosy stigma. In Kumamoto, 157 patients living near Honmyoji were "arrested" and transferred to other sanatoriums. A patient received unjust procedures and was sentenced to the death penalty.

  War and leprosy

• In Japanese sanatoriums, in 1945, because of food shortage, many patients died of tuberculosis in mainland Japan with a rate of 20% at the worst leprosaria. In Okinawa, more than 25% of patients died in the sanatorium in the same year. In the Miyako Nanseien, Okinawa, the death rate was over 40% in 1945 and the cause of death was almost always malaria. It was reported that in a psychiatric hospital in Tokyo, the death rate in 1945 was 40%

  *The rate of death of impatients at 10 national sanatoriums

• In 1945 and 1946, excluding Suruga Sanatorium
• In other years, including all sanatoriums. Amami Wakoen Sanatorium, Okinawa Airakuen Sanatorium and Miyako Nanseien Sanatorium are excluded.

  The 1953 Leprosy Prevention Law and Patients' Struggle

• Kensuke Mitsuda stated before the Upper House in 1951 that all patients be hospitalized. This was a segregation policy and all patients were against it. Some of them staged even hunger strikes, but the 1953 leprosy prevention law was passed; there were practically no changes from the strict 1931 leprosy prevention law.

  The expressed view of the Japan Leprosy Association

• Hiroshi Shima, Fujio Otani, Minoru Narita and Kunio Murakami were primary movers in the abolition of Japan's Leprosy Prevention Law. It was delayed because the opinions of patient autonomy associations differed.

  The statement of the Japanese Leprosy Association on the Leprosy Prevention Law

• It is said that the leprosy control method in Japan was greatly influenced by the First International Congress of Leprosy in 1897, at which it was concluded that isolation of patients was the best method of leprosy control. However, this did not mean indiscriminate isolation of patients. The Interior Ministry of Japan replied to a question that "the salvation of wandering patients" be given priority, above that of prevention. Absolute isolation has been based on two views; 1) that leprosy occurs through intimate contact within the families in which any patients would be the source of infection, and 2) leprosy would be incurable for the rest of life. Absolute isolation was supported by the social belief of that day; leprosy is a shameful disease and the purity of the nation should be maintained, thus justifying isolation. Complete isolation was given priority rather than salvation of patients.
• In Japan, not a small number of patients had been found during the draft for military service. Between 1897 and 1937, leprosy patients found at the draft kept decreasing. There were major national censuses between 1919 and 1935, during which the number of leprosy patients kept decreasing. Epidemiologically speaking, improvement in the living conditions has been given credit for this decrease, rather than the results of isolation. Japan was on its way to elimination of leprosy patients, irrespective of enforced isolation. In other words, statistically speaking, the present leprosy prevention law had not been necessary.
• Nevertheless, the 1953 revision of the leprosy prevention law was passed and enforced. At that time, the effects of chemotherapy were apparent, and internationally, isolation has not been supported at the Rome Conference on rehabilitation. Dapsone and rifampicin were put into service. In 1982, the infectivity of Mycobacterium leprae was found to disappear within several doses of rifampicin, and a multidrug therapeutic regimen was proposed. This has become the standard regimen for leprosy control. Recently new quinolones were added.
• Outpatient treatment has become possible even at the onset of the disease, and now we can treat patients with erythema nodosum leprosum and leprous neuritis without much difficulty.
• Although there have been mysteries left unsolved concerning leprosy, such as the mode of transmission or the relationship between infection and development of symptoms, there have been no reports suggesting leprosy is beyond the concept of ordinary infections.
• Therefore, the present law lost its basis for existence; medically speaking, the law deserved to be abrogated.
• As late as 1955, 91 percent of leprosy patients were hospitalized in leprosaria. Outpatient treatment did become popular, but management of patients continued to be leprosarium-centered. This does not go hand in hand with WHO, which aims at the coexistence of patients and society. Therefore, we have been left far from the remainder of the world. *It cannot be denied that the isolation within the leprosaria has made those working at hospitals and universities lose interest in the treatment of leprosy. The Japanese Leprosy Association deeply reflected on these matters. However, they did not lead toward an abrogation of the outdated law, they did not point out this failure of leprosy control, because those working in leprosaria occupied the central part of the association, and they let the law to exist to the present time.
• New leprosy patients should be treated on an outpatient basis, within the framework of the health insurance system. Hansen's disease centers should be established and specialists be trained.
• We have no right to condemn our senior leprologists who advocated isolation under the banner of "salvation" of the patients. However, we must listen to and hear the pitiful cries of those who have been separated from their families because of leprosy stigma. Reflections and self-criticisms are urgently needed.
• Leprosy control should be nothing but medical control. It was our failure that we advocated isolation with a view to arousing public opinion, thereby stirring up the fear of leprosy in this country. The Japanese Leprosy Association and Japanese medical world need to reflect on this and recognize this fact again.

  The trials

• The Zenkankyo staged a number of struggles against the Ministry of Welfare and they finally won the abolishment of the 1953 Leprosy Prevention Law in 1996. It was ruled that the law was unconstitutional between 1960 and 1996. During this period, the law should have not been present. In 1998, many patients sued the Government for compensation and they won it in 2001.

  Leprosy prevention law

Leprosy Prevention Law of 1907

• The patients who do not have supporting men and women shall be treated in public leprosaria. Those who have supporters shall be cared for by them.

  Leprosy Prevention Law of 1931

• Patients with leprosy shall be hospitalized in leprosaria. Patients should not be engaged in works which may transmit leprosy. The families of patients shall be given some financial aids. The privacy of patients should be respected by physicians and related workers.

  Leprosy Prevention Law of 1953

• Article 1. The aim of the law is to prevent the spread of leprosy, to provide medical care and to promote the welfare of leprosy patients, thus contributing to the general public health.
• Article 2. The national government and local public bodies shall, at all times, strive to prevent leprosy, to provide medical care for leprosy patients and to promote the welfare of the patients. These bodies shall also try to disseminate accurate knowledge of leprosy.
• Article 3. No one shall discriminate the patients or those related to the patients because of this disease.
• Article 4. After a physician has diagnosed the examinee as patient, or after examining or performing autopsy on the dead body of the patient, the physician must, as stipulated by the Ministry of Health and Welfare Ordinance, instruct the method of disinfection and other preventive measures to the patient, his guardian, those living with the patient, those in charge of the premises where the dead body is or was found, and shall also notify within 7 days the particulars stipulated by that Ordinance to the Prefectural Governor of the place of residence of the patient, or the premises where the dead body was found.
• Article 5. When the Prefectural Governor finds it necessary, he may ask a designated physician to examine a patient or one who is, with sufficient reasons, suspected of being patient.
• *2. The physician indicated in the preceding paragraph shall be selected from among those with more than three years' experience in leprosy work and after obtaining consent of the said physician.
• Article 6. When the Prefectural Governor finds that a patient may communicate leprosy, the Governor may encourage the patient or his guardian that the patient be hospitalized in a national leprosarium established by the National Government.
• *2. If the patient or his guardian does not follow this encouragement, as stipulated in the above paragraph, the Prefectural Governor may order the patient or his guardian to be hospitalized for a fixed period of time.
• *3. When one who has been ordered to be hospitalized fail to comply with this disorder, or when there is no time to follow the necessary procedures for hospitalizing the patient in a leprosarium in the interest of public health, as stipulated in the preceding paragraph, the Governor may send the patient directly to a national leprosarium.
• Article 15. The in-patients may not leave the national leprosarium and may be allowed to leave only in the following instances.
• * that there is a special condition such as the death, serious illness, or afflictions of relatives, and when the director grants permission in the view that the patient's going out does not affect the prevention of spread of leprosy seriously. omitted.
• Article 16. The in-patients shall devote themselves to the treatment and abide by the rules of the leprosarium.
• *2. When an in-patient violates the rules of the leprosarium, the director may impose the following punishments on the patient concerned, in order to maintain order within the leprosarium.
• ** To give a warning to the patient;
• ** To confine the patient for a term not exceeding 30 days.

  Laws repealed

The Japanese sanatoriums

13 national sanatoriums

• Matsugaoka Hoyoen.
• *Aomori-ken Aomori-shi ishie, 1909-
• **
• **
• Tohoku Shinseien.
• *Miyagiken Tobe-shi, Sako-machi, 1939-
• **
• Kuryu Rakusen-en
• *Gunma-ken Azuma-gun Kusatsu-cho,1932-
• **
• Tama Zenshoen.
• *Tokyo-to Higashimurayama-shi, 1909-
• **
• Suruga Ryoyosho.
• *Shizuoka-ken Getenba-shi, 1944-
• **
• Nagashima Aiseien.
• *Okayama-ken, Setouchi-shi,1930-
• **
• Oku Komyoen.
• *Okayama-ken, Setouchi-shi,1938
• **
• Ooshima Seishoen.
• *Kagawa-ken Kida-gun Aji-cho,1909-
• **
• Kikuchi Keifuen.
• *Kumamoto-ken Koushi-shi, 1909-
• **
• **
• **
• Hoshizuka Keiaien.
• *Kagoshima-ken Kanoya-shi,1935-
• **
• Amami Wakoen.
• *Kagoshima-ken Amami-shi, 1944-
• **
• Okinawa Airakuen.
• *Okinawa-ken Nago-shi, 1938-
• *
• Miyako Nanseien.
• *Okinawa-ken Miyakojima-shi, 1931-
• **

  Private sanatoriums

• Kouyama Fukusei Byoin
• *The spelling of the hospital
• *For pronunciation, "Kohyama Fukusei Hospital" and "Kōyama Fukusei Hospital" are better. But Koyama Fukusei Hospital is described in a reference.
• **Shizuoka-ken Getenba-shi, 1889-
• **
• Tairoin Shinryosho
• *Kumamoto-ken Kumamoto-shi, 1898-
• **Tairoin Hospital
• **

  Previous sanatoriums

• Name of Sanatorium/Hospital
• *Place
• **Founder or related persons
• Kihai Byoin 1875–1907?
• *Tokyo
• **Masafumi Goto
• Yoikuin
• *Tokyo
• **
• Ihaien 1894–1942
• *Tokyo
• **Kate M. Youngman
• Kaishun Byoin 1895–1941
• *Kumamoto
• **Hannah Riddell
• Jinkeien 1906–1992
• *Yamanashi-ken
• **Ryumyo Tsunawaki
• St. Barnaba Home 1916–1941
• *Gunma-ken
• **Cornwall Legh
• Suzuranen 1926–1931
• *Gunma-ken
• **Kesako Hattori
• Manchuria Sanatorium Doukouin 1939–1945
• *Tetsurei-ken, Manchuria
• **

  Other facilities

• National Hansen's Disease Museum
• *Tokyo-to Higashi-murayama-shi.
• National Infection Research Center. Leprosy Research Center.
• *Tokyo-to Higashi-murayama-shi.
• Okinawa-ken. Yuuna Kyokai
• *Okinawa-ken Naha-shi.

  Life in the sanatoriums

The present situation

• There are about 2600 ex-patients in 13 national Hansen's disease sanatoriums and 2 private hospitals as of May 1, 2009. There are no active leprosy patients, and all are recovered or have after-effects of leprosy. Their mean age is 80. Because of sterilization and abortion, they do not have children. Many of them have diseases of advanced ages or handicaps and aids are necessary. Some earnestly hope for social rehabilitation, but there are very few who are active in society.
• Those in the sanatoriums enjoy life in or out of the sanatoriums; medical and living care are helped by doctors and health workers. Their families visit them in sanatoriums and vice versa. They may be treated in other medical facilities, if necessary.

  Religions

• Every leprosy sanatorium in Japan has churches and Buddhist temples, and it is true that patients had faith, though some patients stated that deciding on religion was in preparation for their death in the leprosaria. In days gone by, they could not share the family graves, an instance of leprosy stigma. In Kikuchi Keifuen Leprosarium, statistics showed Buddhism A 757, B 85, C 89, D 51, Shintoism A 11, Shintoism B 9, Catholic 51, Christianity 95, as of 1979.

  Abortions and sterilization

• Since 1915, sterilization had been performed in public sanatoriums in Japan, since it was hard to bring up the babies born of patients in sanatoriums. Married life was permitted. Abortions were also performed. Because of this custom, patients did not have children.
• The Leprosy Prevention laws of 1907, 1931 and 1953, the last one only repealed in 1996, permitted the segregation of patients in sanitariums where forced abortions and sterilization were common,, and authorized punishment of patients "disturbing peace".

  Recreations

• Hospitalized patients in prewar days were comparatively young, and they enjoyed sports and other kinds of recreations.

  Literature

• Some patients wrote novels, and many patients composed Tanka and Haiku, a short poem.

  Education

• Education in prewar days was unsatisfactory. Educated patients taught patients who needed education. In postwar days, branch schools of primary schools and secondary schools were made within the leprosariums. A high school was made for some time starting in 1955; 369 patients were enrolled and 307 patients graduated from the school.
• Education of children born of patients was insufficient. In Kumamoto, the enrollment of them into a primary school met social stigma or leprosy stigma in 1954 which was called the Tatsudaryo Incident or Kurokamikou Incident.

  Leprosy stigma

• Leprosy in Japan is characterized by considerable leprosy stigma, by the Buddhistic concept of leprosy that leprosy is punishment and in modern times by three leprosy prevention laws requesting segregation.

  Personalities

Empress Teimei

• Empress Teimei, also known as Empress Dowager Teimei, was empress consort of Emperor Taishō of Japan. She was the mother of Emperor Shōwa. Her posthumous name, Teimei, means "enlightened constancy". She was interested in leprosy problems and donated money to Hannah Riddell in financial distress since 1915, and other foreigners. She donated money with which a leprosy prevention foundation was established in 1931 and left money upon her death which became the basis of the Tofu Organization for Leprosy, in 1951.

  Kensuke Mitsuda

• Kensuke Mitsuda The most influential leader both in the administration of leprosy policy and the academic circle.
• *He stated that all leprosy patients be hospitalized before the Upper House in 1951, and led to the 1953 leprosy prevention law. As a scholar, he found a lepromin reaction called Mitsuda reaction or Mitsuda test. This is very important in the classification of leprosy.

  Hannah Riddell

• Hannah Riddell was an English woman who devoted her life to the salvation of Hansen's disease patients in Japan. She not only established "Kaishun Hospital", the first leprosy hospital in Kumamoto, but also inspired the conscience of the Japanese people on this problem.

  Mary Cornwall-Legh

• Mary Cornwall-Legh was a highly educated English woman who devoted herself, after age 50, to missionary work in Japan and especially to the welfare, education and medical care of leprosy patients in Kusatsu, Gunma Prefecture, Japan.

  Keisai Aoki

• Keisai Aoki. A Japanese missionary who virtually paved the way to the establishment of Hansen's disease sanatorium Kunigami-Airakuen, Okinawa, with extraordinary difficulties. At age 16, he developed leprosy and later, under the leadership of Hannah Riddell, he helped people with leprosy in Okinawa.

  Matsuki Miyazaki

• Matsuki Miyazaki The director of the Kyushu Sanatorium. He studied the war and leprosy and by his efforts, soldiers who developed leprosy could receive the same treatment as those who developed tuberculosis. He was a segregationalist. After retiring from the Kikuchi Keifuen Sanatorium, he established a leprosy facility in India. He died in an airplane accident in India.

  Isamu Masuda

• Isamu Masuda was a Japanese doctor, known for writing "Leprosy and Social Problems" in 1907, the year of the promulgation of the first leprosy law, and openly criticized the crucial segregation policy. He advocated the nation's involvement in the discovery of treatments of leprosy, since he believed that it was curable.

  Masako Ogawa

• Masako Ogawa was a female Japanese doctor who worked at the Nagashima Aiseien Sanatorium. She wrote a book, "Spring in a small island" in 1938, about her experiences in persuading leprosy patients in remote areas of Japan into hospitalization. It created a sensation in Japan, and was made into a film. On the other hand, she was criticized for accelerating the "No leprosy patients in prefecture" movement and giving the impression that leprosy is to be feared.

  Masasue Suho

• Masasue Suho was a Japanese physician, the director of the Sorok Island Sanatorium in Korea. He completed the world's biggest leprosy facility Sorok Island Sanatorium hospitalizing 6000 patients. He was assassinated by a patient while rushing to a morning ceremony. Forced segregation of leprosy patients, the worsening of treatment of patients and antipathy against colonial rule were behind the assassination.

  Ryumyo Tsunawaki

• Ryumyo Tsunawaki (January 24, 1876 – December 5, 1970, was a Buddhist priest who established a leprosy hospital Minobu Jinkyo-en, in Minobu-cho, Yamanashi-ken, Japan in 1906.

  Noboru Ogasawara

• Noboru Ogasawara was a Japanese physician specializing in leprosy. He was an assistant professor at the Department of Kyoto Imperial University. He insisted that leprosy was not incurable and diathesis was an important factor in the development of leprosy. He was against strict segregation of leprosy patients and met strong opposition at a Congress of leprosy.

  Masanao Goto

• Masanao Goto, was a Japanese leprologist. He was the son of first Shobun Goto and called as the second Shobun Goto. He devoted his life to leprosy patients in Japan and on the island of Molokai in the Kingdom of Hawaii. Father Damien had trust in Goto's therapy, and he left the message, "I have not the slightest confidence in our American and European doctors to stay my leprosy, I wish to be treated by Dr. Masanao Goto."

  Mosuke Murata

• Mosuke Murata was a Japanese dermatologist who was the designator of erythema nodosum leprosum in 1912.

  Mieko Kamiya

• Mieko Kamiya was a psychiatrist who treated leprosy patients at Nagashima Aiseien Sanatorium. She was known for the translation of books on philosophy. She was said to be "one of doctors of the Department of psychiatry of Tokyo University soon after the war", who "greatly helped the Ministry of Education and the General Headquarters as English-speaking secretary", and to be "an adviser to Empress Michiko". She wrote many books as a highly educated, multi-lingual person; one of her books titled on the meaning of life based on her experiences with leprosy patients attracted many readers.

  Kazuo Saikawa

• Kazuo Saikawa was a Japanese physician, who contributed to the treatment of leprosy and to the administration of leprosy policy in Japan. He was against Kensuke Mitsuda and worked in Taiwan and Okinawa.

  Heibei Okamura

• Heibei Okamura produced Japan's finest "Okamura's" chaulmoogra oil, between about 1892 and 1944 at Sakai, Osaka, Japan. The chaulmoogra oil had been the only one remedy in wide use before Guy Henry Faget proved the efficacy of promin in 1943. Promin started the era of sulfur chemicals and revolutionalized the treatment of leprosy. Okamura was also known for caring for more than 1,000 leprosy patients between 1888 and 1901 in his house.

  Suketoshi Chujo

• Suketoshi Chujo was a Japanese physician, a Hansen's disease researcher, the first director of Matsugaoka Hoyoen Sanatorium. He repeatedly reported turpentine spirit preparation he named TR as effective for leprosy.

  Isamu Tajiri

• Isamu Tajiri was a Japanese physician specializing in leprosy. He worked at Nagashima Aiseien Sanatorium, Kikuchi Keifuen Sanatorium and Tama Zenshoen Sanatorium. In 1955, he proposed "acute infiltration" of leprosy.

  Shigetaka Takashima

• Shigetaka Takashima was a Japanese physician and studied leprosy. He worked in Kuryu Rakusen-en Sanatorium, Tohoku Shinseien Sanatorium, Suruga Sanatorium and Nagashima Aiseien Sanatorium.

  Fumio Hayashi

• Fumio Hayashi was a Japanese physician and leprologist. He worked in Tama Zenshoen Sanatorium, Nagashima Aiseien Sanatorium, Hoshizuka Keiaien Sanatorium and Ooshima Seishoen Sanatorium. He helped with Kensuke Mitsuda, and completed the first lepromin test or Mitsuda skin test.

  Kageyoshi Tada

• Kageyoshi Tada was a Japanese physician who worked in Miyako Nanseien Sanatorium, Okinawa Prefecture Japan between 1938 ad 1945. He put in-patients who were forcibly hospitalized under strict control. Barbwired fences were built around the sanatorium and a special prison was also built, not to allow in-patients to go out of the sanatorium. In 1945, 110 in-patients died of malaria, malnutrition and as direct effects of air attacks, while his group escaped to the army shelter.

  Kohsaburo Iesaka

• Kohsaburo Iesaka 家坂幸三郎 was a Japanese Christian physician who headed the Miyako Nanseien Sanatorium and Okinawa Airakuen Sanatorium. The church he created as "Yomigaerino Kai" still remains in the Miyako Nanseien Sanatorium, as well a s a church of Nippon Sei Ko Kai and a catholic church.

  Mamoru Uchida

• Mamoru Uchida was an ophthalmologist who worked for leprosy patients at Kyushu Sanatorium Nagashima Aiseien Sanatorium, and Matsuoka Hoyoen Sanatorium. He taught leprosy patients "Tanka", in these sanatoriums. Later, he studied social welfare as professor at Kumamoto Junior College. He extensively studied the history of leprosy, and presented many documents to the Kumamoto Prefectural Library. 338 items were shown at an exhibition of Hansen's disease and literature in 2003.

  Shunsuke Miyake

• Shunsuke Miyake was born in Shimane Prefecture and was qualified as a doctor. He practiced in Tsuwano, Yamaguchi, Nagasaki, and Taniyama. He was baptized in Yamaguchi Prefecture and did missionary work. He was asked to work at Kaishun Hospital by Hannah Riddell in 1897 and lived in the hospital until his death for 30 years. He worked as a buffer between Hannah Riddell and patients, although he looked as if he was a servant of the hospital. He was loved by patients.

  Takekichi Sugai

• Takekichi Sugai was the first chief doctor at Sotojima Hoyoen Sanatorium who wrote many papers on leprosy. Sotojima Hoyoen was a public leprosy sanatorium present in Osaka Prefecture between 1909 and 1934.

  Koh Yasuda

• Koh Yasuda was a Japanese ophthalmologist who became the first director of Amami Wakoen Sanatorium, a leprosy sanatorium in Amami Ōshima, Kagoshima Prefecture, Japan. He was drafted into military service and died in China in 1943.

  Taiji Nojima

• Taiji Nojima （のじま たいじ,1896–1970) was a Japanese dermatologist at Ooshima Seishoen Sanatorium, for 41 years,. He attended many international leprosy congresses and visited many overseas leprosy sanatoriums.

  Hakaru Miyagawa

• Hakaru Miyagawa worked at Zensho Hospital, Tama Zenshoen Sanatorium, Nagashima Aiseien Leprosarium, Nagashima Aiseien Sanatorium, Okinawa Airakuen Leprosarium, Okinawa Airakuen Sanatorium and Hoshizuka Keiaien Leprosarium, Hoshizuka Keiaien Sanatorium and studied the history of leprosy.

  Foreigners who worked for leprosy care

• Baelz, Erwin Germany 1876–1905
• Bertrand, Joseph Jean Augustin France 1890–1916 Fukusei Byoin
• Cornwall Legh, Mary Helena England 1908–41
• Corre, Jean Marie France 1875–1911 Tairoin
• Drouart de Lézey, Lucien France 1873–1930 Fukusei Byoin
• Kidder, Anna H. USA 1875–1913 Ihaien
• Magill, Mary B. USA 1907–37
• Oltmans, Albert USA 1886–1939 Ihaien
• Riddel, Hannah England 1873–91 Kaishun Byoin
• Testvuide, Germain Léger France 1872–92 Fukusei Byoin
• Vigroux, Francois Paulin France 1872–93 Fukusei Byoin
• Whitman, M. Antomelle USA 1886–1917 Ihaien
• Wirik, Loduska J. USA 1890–1914 Tokyo
• Wright, Adeleid, Hannah England 1896–1950 Kaishun Byoin
• Wyckoff, Martin Nevuis USA 1872–1911 Ihaien
• Youngman, Kate M. USA 1890–1942 Ihaien
• Five Sisters at Tairoin France, Canada 1898- Tairoin