Edel was born in Pittsburgh, Pennsylvania, the son of Fannie and Simon Edel. Edel grew up in Yorkton, Saskatchewan. He attended McGill University and the Université de Paris. While at the former he was associated with the Montreal Group of modernist writers, which included F.R. Scott and A.J.M. Smith, and with them founded the influential McGill Fortnightly Review. Edel taught English and American literature at Sir George Williams University, New York University, and at University of Hawaii at Manoa. For the academic year 1965-1966, he was a Fellow on the faculty at the Center for Advanced Studies of Wesleyan University. Though he wrote on James Joyce and on the Bloomsbury group, his lifework is summed up in his five-volume biography of Henry James. Edel discussed the notion of biography in literary biography, in particular his conviction that literary biography should enfold a subjective author's self-perceptions into his output. Edel's second and third volumes of the James biography earned him the 1963 Pulitzer Prize for Biography or Autobiography and a National Book Award for Nonfiction in 1963. Edel enjoyed privileged access to letters and documents from James' life housed in the Widener Library at Harvard University, after gaining the blessing of members of James' family. He referred to other scholars who sought access in vain as 'trespassers'. The discovery of impassioned but inconclusive letters written in 1875-1876 by James to the Russian aristocrat Paul Zhukovski, while Edel was deep in the process of finishing his biography caused an ethical crisis; his decision was to continue to ignore what he considered a peripheral aspect of the self- identified "celibate" and sexually diffident James's life. Edel did treat James's relationships with novelist Constance Fenimore Woolson and sculptor Hendrik Christian Andersen at length, especially in volumes three and four of the biography. After weighing all the evidence, Edel confessed that he was unable to decide whether James experienced a consummated sexual relationship. Although later scholarship and new materials have called into question the accuracy of his portrait of James, Edel's work remains an important source for studies of the author. In October 1996, about a year before Leon Edel died, Sheldon M. Novick published Henry James: The Young Master. Novick's volume "caused something of an uproar in Jamesian circles" as, like other more recent biographies of Walt Whitman and John Singer Sargent, it challenged the notion, deriving from a once-familiar paradigm in biographies of homosexuals when direct evidence was non-existent, that James lived a celibate life. Novick also criticized Edel for following a discounted Freudian interpretation of homosexuality "as a kind of failure." The difference of views led to a series of exchanges between Edel and Novick that were published by Slate.