, the founding father of the family, was a prominent pachter or revenue farmer in Batavia between 1845 and 1861, as well as one of the city's wealthiest tycoons. He was also part of the powerful Ngo Ho Tjiang partnership that dominated the opium monopoly in Batavia. He served as Wijkmeester of Meester Cornelis, a junior position in the civil bureaucracy. While Lauw Ho failed to secure an elevation to the prestigious Chinese officership, which was a high-ranking civil government post, his two sons – Lauw Tek Kang and Lauw Tek Lok – were both appointed Luitenants der Chinezen of Meester Cornelis and Bekasi respectively on December 23, 1854. They also became important Landheeren or landlords through their acquisition of significant agricultural landholdings in the Ommelanden or rural hinterland of Batavia, including the estate of Tjimanggis. The brothers' acquisition of Chinese lieutenancies and landed estates marked their entry into the ranks of the Cabang Atas. Luitenant Lauw Tek Lok, who served in office with distinction until his death in 1882, nonetheless caused some consternation among the colonial authorities due to his unconventional, interracial marriage with an Indo-Bohemian woman, Louisa Zecha. On being widowed in 1882, Zecha further scandalized colonial society by marrying her dead husband's former private secretary-turned-magnate Sim Keng Koen, who later had a distinguished government career as the first Kapitein der Chinezen of Sukabumi, a colonial hill station in the Preanger highlands of West Java. As the historian Mely G. Tan notes, the Lauw-Sim-Zecha family lived in a grand style as the premier gentry family of Sukabumi, where most of the extended clan settled down.
Luitenant Lauw Tek Lok and Louisa Zecha's grandson, Aristide William Lauw-Zecha, became the first Indonesian-born graduate of an American university, and was a prominent plantation owner. Kapitein Sim Keng Koen and Louisa Zecha's youngest son, Chester Lauw-Sim-Zecha, was also an important community and business leader, as well as a Freemason, in the first half of the twentieth century. The family, however, lost their vast landholdings and assets due to the Indonesian Revolution and President Sukarno's nationalization of private landed estates in 1952. In the aftermath of the revolution, many members of the Lauw-Sim-Zecha family, like other scions of the Cabang Atas, left Indonesia and settled overseas. Notable members of the family today include the Malaysian royal Che Engku Chesterina and her cousin, Adrian Lauw-Zecha, son of A. W. Lauw-Zecha and the founder of Aman Resorts. Lauw-Zecha's son, Ajai, is married to the Singaporean actress Michelle Saram.
