In Boston, the Ladies’ Physiological Institute was formed in 1848. A course of lectures was given that year on the “laws of life and health,” by Professor Bronson, which aroused so much interest that at the close, an organization was formed with him at the head, and with the expressed purpose of promoting among women's knowledge of the human system, the laws of life and health, and the means of relieving sickness and suffering. Several of the most advanced women of the time became members and 400 women joined the organization. Bronson was the first president, but in 1850, Cobb was made president. In 1850, Cobb, Ann M. Kendall, C. E. N. Kimball, Sarah Goodridge, and Rebecca W. Cleverly incorporated the organization for the purpose of promoting, among women, a knowledge of the human system, the laws of life and health, and the means of relieving sickness and suffering. The society met with much opposition, as it was considered immodest and almost disreputable for women in that day to be interested in anatomy and hygiene. For several years, only one minister could be found in Boston who would make a prayer for them at a public meeting. After the first women physicians became established in Boston, a feminine member of the medical profession was always chosen for president; but in spite of its bad name, the character of the women who made up the club, — the most advanced and liberal of the mid-19th century,— brought the organization through its doubtful period and won entire respect from the community. From the beginning, the Institute, as it was called, held weekly or fortnightly meetings, with lectures on physiology, hygiene, and sanitation, and many of the leading physicians and ministers of New England spoke before this body. The duty of parenthood, the science of reproduction, the sacredness of the home were taught to thousands of young women, and an unbroken record of 60 years of earnest work was credited to the Ladies’ Physiological Institute. The club joined the Massachusetts State Federation in early years, and was the first to open the movement which resulted in the Committee of Council and Co-operation, a body composed of delegates from other important clubs to work together for the public good in whatever way suggested itself from year to year, such as the establishment of houses of detention and police matrons. Another early Massachusetts club which existed for approximately 50 years was the Moral Education Society, along similar lines, merged with the Ladies’ Physiological Institute.