Lü was born in a village administered by Qianjiang City, Hubei Province. His father, Lü Yuan, and the rest of his family were farmers. When he was 13 years old he joined a local sports school to be trained as a weightlifter, which was an opportunity to escape rural poverty. In 1999, to remove the financial burden on Lü's family, his coach Dengling Hu sent him to join the provincial team.
Weightlifting career
In 2003 Lü represented the Hubei provincial team in the Chinese national weightlifting championships, competing at 69 kg. He won the bronze total for his class. The same year, due to his outstanding performance, he was recruited by the Chinese national team. In 2006 due to ligament injuries in his shoulders and legs, he left the national team. In 2008, after the 2008 Summer Olympics, Lü renewed his training in the national team with coach Yu Jie. He has set 12 senior world records throughout the course of his career.
Olympics
Heading into the 2012 Summer Olympics Lü was the heavy favorite to win. He ended up winning the gold medal at the 2012 Summer Olympics in the 77 kg class with a total of 379 kg. His snatch of 175 kg set both a world and Olympic record, as did his total of 379 kg, for the 77 kg class. Due to an error during the snatch phase, Lü was unable to attempt his third lift at 177 kg. He was again the heavy favorite to win gold at the 2016 Summer Olympics. He finished the snatch phase with a new world record of 177 kg, but did not win gold due to Nijat Rahimov'sclean and jerk world record of 214 kg. Lü and Rahimov had the same total, but Rahimov won due to virtue of a lighter body weight.
World Championships
In 2009 he won his first World Weightlifting Championships where he set new Snatch and Total world records. Looking to repeat in 2010 he ended up being the silver medalist, but returned in 2011 to win gold for the second time. Lü won 3 gold medals in the 77 kg class at the 2013 World Weightlifting Championships. He broke his own world record in the snatch with a lift of 176 kg. He also completed a 204 kg clean and jerk, setting a new world record total of 380 kg. At the 2015 World Weightlifting Championships he won the gold medal in the snatch, but was unable to complete a clean and jerk which eliminated him from winning a fourth world championship. In 2018 the International Weightlifting Federation updated the weight classes, and he competed in the newly created 81 kg division. The 81 kg division saw 5 world records set and 11 junior world records set. In the snatch portion, Lu initially set the snatch world record of 172 kg, then Mohamed Ihab in his next attempt lifted 173 kg setting a new world record. In the clean & jerk portion, Mohamed Ihab set 2 new world records in the total with his first two lifts, but he was unable to lift his final clean & jerk of 203 kg. This allowed Lu to win gold with his 202 kg clean & jerk, setting a new world record total of 374 kg, out lifting Mohamed Ihab by 1 kg.
Personal life
Lü married his long-term girlfriend Guo Xiyan, a former world class weightlifter herself, in December 2013. They have one child together, born in August 2014.