As Minister for Women and Child Development, Tirath stated that the government's priorities would be to "support holistic empowerment of women, ensure adequate and universal availability of supplementary nutrition for children, adolescent girls and expectant mothers and build a protective environment for children where they can develop and flourish as responsible and happy citizens of the society." Tirath has proposed that working Indian husbands pay a portion of their income to their wives. The goal is to calculate the value of housework, and to socially empower women for the work they do at home. In a 2012 meeting with United States Secretary of Health and Human ServicesKathleen Sebelius, Tirath stated her concern for malnutrition among children in India. She emphasized the importance of agencies like Integrated Child Development Services for implementing improvements in education, immunization and supplementary nutrition, to alleviate child mortality.
On 24 January 2010 a photograph of former Pakistan Air Chief Marshal Tanvir Mahmood Ahmed in uniform appeared along with those of Prime Minister Manmohan Singh and Congress president Sonia Gandhi in a full-page newspaper advertisement given by Ministry of Women and Child Development to mark the National Girl Child Day. Initially Mrs.Tirath refused to accept the error on behalf of her ministry, accused the media of hair-splitting, and stated, " message is more important than the image. The photograph is only symbolic. The message for the girl child is more important. She should be protected." She later apologised on behalf of her ministry for publishing a photograph of a former Pakistan Air Force chief in a government advertisement and said an inquiry will bring out who was responsible for it. The former air marshal, upon learning of the publication, "..wasn't aware about this an innocent mistake."
Controversy over misuse of power
On 13 September 2010, Central Administrative Tribunal cancelled the appointment of Krishna Tirath's daughter Yashvi Tirath for the post of anchor-cum-correspondent in state run telecaster Doordarshan News. A tribunal, headed by chairman V K Bali, cancelled the selection of the journalists working with DD News, finding "misuse of marks in the interview" and "irregularities having vitiated the whole process."
Joining BJP
On 19 January 2015, she formally joined the BJP after meeting Mr Amit Shah - the BJP President. She contested from Patel Nagar as a BJP candidate for the 2015 Delhi Legislative Assembly election and was defeated by Hazari Lal Chauhan of AAP by a margin of 34,638 votes. She left the Bharatiya Janata Party in March 2019 and rejoined Indian National Congress.