Keko was born in Brunete, Community of Madrid. A product of hometown Atlético Madrid's youth ranks, he made his first-team – and La Liga – debut on 12 September 2009, taking the field as a 63rd-minute substitute in a 1–1 home draw against Racing de Santander, aged just 17. Speaking to Diario AS after the match, he said: "The truth is that I have always dreamed of playing in this stadium, despite the draw, it was a dream come true. I did not think about the protests outside the ground, and I only wanted to score. I hope to have more chances, but I have to be calm and see what the coach decides." Late in January 2010, Keko was loaned to fellow league clubReal Valladolid until the end of the season. He made his debut for his new team against Valencia CF, appearing as a late replacement in an eventual 0–2 away loss on 6 February. Keko split the 2010–11 campaign with two Segunda División sides, FC Cartagena and Girona FC, appearing in 25 matches combined as both managed to retain their league status.
Catania
On 19 July 2011, after he failed to renew his contract with Atlético Madrid, Keko completed a transfer to Calcio Catania in Italy, signing a three-year deal and being awarded the No. 15 jersey at the Sicilian club. On 7 January 2012, however, along with teammate Fabio Sciacca, he joined Serie B's U.S. Grosseto F.C. on loan. Keko scored on his Serie A debut on 24 February 2013, starting and contributing to a 2–1 away win over Parma FC. In May 2014, he was released.
On 9 July 2015, Keko moved to SD Eibar in the top division after agreeing to a two-year contract. He scored his first goal in the competition on 30 December, netting the first in a 2–0 home win against Sporting de Gijón.
Málaga
On 21 June 2016, Keko joined Málaga CF on a four-year deal. He appeared in 22 scoreless matches in his first season, helping his team finish in 11th position. On 29 July 2018, after suffering relegation, Keko agreed to a one-year loan deal back at former club Valladolid, now in the top flight. On 31 January 2020, he terminated his contract with the Andalusians.
Deportivo
On 31 January 2020, just hours after leaving Málaga, Keko signed a two-and-a-half-year deal with Deportivo de La Coruña, still in the second tier.
