KMT5A
N-lysine methyltransferase KMT5A is an enzyme that in humans is encoded by the KMT5A gene. The enzyme is a histone methyltransferase, SET domain-containing and lysine-specific. The enzyme transfers one methyl group to histone H4 lysine residue at position 20. S-Adenosyl methionine is both the cofactor and the methyl group donor. The lysine residue is converted to N6-methyllysine residue.
This histone modification is often abbreviated H4K20me1:
