Sawers joined the Foreign and Commonwealth Office in 1977. In his early career, Sawers worked in Yemen and Syria, on behalf of MI6. He became Political Officer in Damascus in 1982 and then returned to the Foreign and Commonwealth Office to take up the role of Desk Officer in the European Union Department in 1984 and Private Secretary to the Minister of State in 1986. He was based in Pretoria and then Cape Town in South Africa from 1988 to 1991 during the first part of the transition from apartheid. He returned to the Foreign and Commonwealth Office yet again to take up the roles of Head of European Union Presidency Planning Unit in 1991 and Principal Private Secretary to Douglas Hurd in 1993. From 1995 to 1998 he was in the United States and spent a year as an International Fellow at Harvard University and later at the British Embassy in Washington D.C., where he headed the Foreign and Defence Policy team. From January 1999 to summer 2001 he was Foreign Affairs Adviser to UK Prime Minister Tony Blair, dealing with all aspects of foreign and defence policy and working closely with international counterparts. The period included the Kosovo War. He also worked on the Northern Ireland peace process and the implementation of the Good Friday Agreement. He reviewed the Iraq sanctions policy during this period and issued a document that included consideration of regime change. He served two years in the Middle East as Ambassador to Egypt from 2001 to 2003, and for three months was the British Government's Special Representative in Baghdad assisting in the establishment of the Coalition Provisional Authority as the transitional government during the Occupation of Iraq. In August 2003 Sawers was appointed Director General for Political Affairs at the Foreign and Commonwealth Office. In this post he advised the UK Foreign Secretary on political and security issues worldwide and negotiated on behalf of the Foreign Secretary with international partners in the G8, EU and UN. He was particularly involved in policy on Iran, Iraq, Afghanistan and the Balkans. Sawers headed the British team in the EU-3 negotiations over Iran's nuclear program in 2006, utilising his scientific background in discussions of nuclear matters. In 2007 he became British Permanent Representative to the United Nations. Sawers is a governor of the Ditchley Foundation, which aims to promote international, especially Anglo-American, relations.
After retiring as Chief of the Secret Intelligence Service Sawers became Partner and Chairman of Macro Advisory Partners, before becoming the Executive Chairman of Newbridge Advisory. He also became a Visiting Professor in the Department of War Studies at King's College London. He is a member of the Steering Committee of the Bilderberg Conferences and participated in conferences since 2014 He is a Senior Associate Fellow of the Royal United Services Institute. On 14 May 2015 he was appointed independent non-executive director of BP Global.
Private life
Sawers is married; the couple have three children, two sons and a daughter. Sawers enjoys hiking, tennis, cycling and the theatre.