Giella attended the School of Industrial Art in Manhattan. He also studied at the Art Students League in Manhattan, alongside future comics professionals Mike Sekowsky and Joe Kubert, and took commercial art courses at Hunter College. He began working in art at 17, he said in a 2002 interview, explaining that "when your parents are struggling to keep the house going, the first son in the family, especially in an Italian family, had to go to work." He described his first professional job as the humor feature "Captain Codfish", which the interviewer described as "a less-eccentric 1940s ancestor of SpongeBob SquarePants". A standard reference, the Grand Comics Database, lists one "Captain Codfish" feature, running six pages with the art signed by Giella, in Hillman Periodicals' Punch and Judy Comics #11.
Giella later freelanced for Fawcett Comics, commuting by bus to C. C. Beck's and Pete Costanza's studio in Englewood, New Jersey, to ink Captain Marvel stories. In either 1946 or 1947, he began freelancing for Timely Comics, the 1940s precursor of Marvel Comics, and shortly afterwards joined the staff. His start was rocky, however; as a 2012 article related, "I would do any work that they offered," Giella had recalled in a 2005 interview. "I started out doing a little touch-up work, a little background work, a little inking, redraw this, fix this head, do something with this panel". Later, he assisted Syd Shores on Captain America Comics, finishing backgrounds, making pencil corrections and inking occasional pages. Giella did similar duty on Human Torch, Sub-Mariner, and humor stories. Inking soon became his specialty. In 1948, he joined the Naval Reserves, continuing with them for eight years. His friend Frank Giacoia began drawing for DC Comics in the late 1940s, and eventually convinced Giella to join him at that better-paying company. Starting circa 1948, Giella inked stories featuring the Flash, Green Lantern, Black Canary and other characters under editor Julius Schwartz.
Into the Silver Age
During the early-1950s lull in superheroes, Giella inked Westerns penciled by Alex Toth and Gene Colan. When the era called the Silver Age of comic books began with the resurgence of superheroes in 1956, Giella began inking science-fiction stories, including the feature "Adam Strange" in Strange Adventures, and Batman stories pencilled by the likes of Sheldon Moldoff, and Carmine Infantino. In the 1960s, he prominently inked Gil Kane on the series Green Lantern.