Wade was born in Eugene, Oregon. She moved to Los Angeles to pursue her acting career in 1998. In 1999, she debuted on television in the MTV anthology series Undressed. After Neil LaBute recruited her to star opposite Aaron Eckhart in his 10-minute film Tumble, the filmmaker offered her an uncredited role in his 2000 comedy film, Nurse Betty, starring Renée Zellweger. Following her film debut, Wade returned to television, guest starring in an October 2000 episode of the syndicated nonfiction TV program Arrest & Trial and in a January 2003 episode of the comedy series 8 Simple Rules for Dating My Teenage Daughter. She was also cast in the 2003 ABC pilot Naked Hotel starring John Corbett, which was not picked up to series; Wade played the assistant manager at the fictional Hotel de Bleu a Bahamas hideaway. Wade returned to the film in 2005, playing Jane Fonda's young replacement in Robert Luketic's romantic comedy filmMonster-in-Law, which co-starred Jennifer Lopez and Michael Vartan. That same year, Wade appeared in several other films: Wes Craven's drama/thriller Red Eye with Rachel McAdams, Harold Ramis's neo-noir/comedy-drama The Ice Harvest, and the Rob Reiner comedy Rumor Has It with Jennifer Aniston, Kevin Costner, and Shirley MacLaine. Also in 2005 Wade appeared in John Gulager's horror film Feast, which received a limited theatrical release in the United States in September 2006, playing the role of waitress Honey Pie. Wade reprised her role as Honey Pie in the film and a cameo in the film. In 2006, Wade co-starred with John Patrick Amedori, Lizzy Caplan and Daryl Hannah in Elliott Lester's teen drama, Love Is the Drug, playing the role of "haughty" private school student Erin. In 2007, she played the role of sous-chef Leah in No Reservations, Scott Hicks’s remake of the German comedy Mostly Martha, starring Catherine Zeta-Jones and Aaron Eckhart. In 2009 Wade appeared in the film The Strip playing the role of "free-spirited" Melissa. In 2009, Wade joined the cast of The CW comedy series Reaper playing the recurring role of the demon Nina. Earlier the same year she was cast onBody Politic, a well-received CW pilot that was not picked up to series, playing the part of Ruby "an idealistic young staffer". In 2010, she was cast as Assistant District Attorney Liz Traynor on the short-lived Fox buddy-cop series The Good Guys alongside Colin Hanks and Bradley Whitford. In 2011, Wade was cast on the 2012–13 TBS comedy series Wedding Band, playing the role of Rachel the love interest of Brian Austin Green's character.
