The Blue Jays, an expansion team in 1977, did not have a AA team affiliated with their club that season. Instead, they sent Byrd to the Cleveland Indians AA team in the Eastern League, the Jersey City Indians. Byrd had a poor record of 1-4, however, he had a very solid ERA of 3.13 in ten games with the club. The Blue Jays promoted Byrd to Major League Baseball in June of that season. Byrd made his major league debut on June 20, 1977, when he started a game against the Cleveland Indians at Exhibition Stadium. At 20 years old, Byrd became the youngest Blue Jay pitcher to start a game, a distinction he holds to this day. Byrd pitched five innings, allowing three runs, while striking out four hitters, as Toronto lost to Cleveland 6-5. Byrd earned a no-decision in the contest. On June 25, Byrd made his second career start, pitching 7.1 innings, allowing four runs, and took the loss as the Baltimore Orioles defeated Toronto 5-2. In his fourth career start, Byrd pitched six innings, allowing three runs, as Toronto won over Cleveland 5-3 at Cleveland Municipal Stadium, and Byrd earned his first career victory. Byrd would struggle for the rest of the season, picking up only 2 wins in a total of 17 starts. His season ended on a particularly dismal note, as he lost each of his final nine starts, and pitched in only 0.2 innings in his final start, allowing five runs to the Boston Red Sox. Byrd finished the year with a 2-13 record, and an ERA of 6.18. At the end of spring training 1978, the Blue Jays assigned Byrd to their AAA affiliate, the Syracuse Chiefs of the International League. He complained to the press when he was sent down to Triple-A that his minor league salary was less than what he could make doing construction work. At Syracuse, Byrd had a disastrous time of it, making seven starts and posting a 0-3 record and an ERA of 8.13. When the Blue Jays decided to further demote Bryd to Double-A after his poor start in Syracuse, he abruptly left the Blue Jays organization and—proving his point about his minimal minor league baseball salary—spent the rest of the year working at a construction site. Byrd rejoined the team for spring training, 1979, declaring that the previous year was "water under the bridge". However, the Blue Jays released Byrd on March 29, 1979.
In 1979, Byrd spent the season with the San Jose Missions of the California League, which was the Seattle Mariners A level affiliate. Byrd posted a solid record of 12-6 with an ERA of 2.98 in 26 starts. However, wildness continued to be a problem, as in 151 innings, Byrd walked 117 batters, hit 15 others, and threw 17 wild pitches. Byrd ended his career after that season.
