He was elected to Parliament for North Kildare in the Irish Parliamentary Party landslide in the 1885 general election by a large majority over the Conservative candidate, and returned unopposed in the election of the following year. He assisted J. J. Clancy in running the Irish Press Agency in London. During the Land War, in February 1889, he was prosecuted for a speech calling for the boycott of the Earl of Drogheda. Following his arrest, in Perthshire, Scotland, while campaigning in support of a Liberal by-election candidate, he was sentenced to four months' imprisonment and confined in Kilkenny, and later Kilmainham Gaols. When the Irish Parliamentary Party split in December 1890 over the leadership of Charles Stewart Parnell, Carew supported the latter. He then acted as one of the whips of the Parnellite parliamentary party. In the subsequent bitter general election of 1892, he was defeated by an Anti-Parnellite by 56 to 44 per cent. He contested North Kildare again in 1895 and was defeated by the slightly smaller margin of 53 to 47 percent. The following year the opportunity to return to the House of Commons arose when his fellow Parnellite Dr J. E. Kenny resigned the strongly Parnellite seat of Dublin College Green. Carew was selected and returned unopposed. Later in this parliamentary term, Carew came under attack in the Irish Nationalist movement for attending royal functions. He also became associated with the Healyite faction in the House of Commons. Consequently, in 1900, he was opposed in Dublin College Green by a new Nationalist candidate, Joseph Patrick Nannetti. Although the exact circumstances appear to be disputed, he was additionally nominated for his native seat of South Meath, and elected unopposed because the sitting member John Howard Parnell, expecting no opposition, omitted to submit the fees necessary for nomination in a contested election. Carew subsequently stated in a letter to the press that his return at South Meath was secured without his knowledge or consent, and offered to resign in favour of Parnell or any other candidate nominated by the constituency. However he was defeated at College Green and did not resign South Meath. At the subsequent National Convention of the United Irish League, Carew was excluded from the Irish Parliamentary Party, along with Timothy Healy. Whereas Healy was later reconciled, temporarily, with the IPP, Carew did not live long enough for this to occur. He died suddenly three years later, after having recently been appointed High Sheriff of Kildare.