JWH-147


JWH-147 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 11.0 nM at CB1 vs 7.1 nM at CB2. It was discovered and named after John W. Huffman.

Legal status

In the United States, CB1 receptor agonists of the 3-pyrrole class such as JWH-147 are Schedule I Controlled Substances.
JWH-147 was banned in Sweden on 1 October 2010 as harmful to health, after being identified as an ingredient in "herbal" synthetic cannabis products.