I-10 enters Hidalgo County, New Mexico from Cochise County, Arizona as a four lane divided highway. The highway travels east through rural southwest New Mexico, passing between Steins Mountain and Attorney Mountain, part of the Peloncillo Mountains, before passing by the ghost town of Steins. Continuing east, the northern terminus of New Mexico State Road 80 is intersected, serving Rodeo, followed by NM 338. Passing Lee Peak the highway turns southeast entering Lordsburg. US 70 is intersected in town, and becomes concurrent with the highway as it continues east past the Lordsburg Municipal Airport, before exiting the town. Near the Grant County line the highway bypasses the ghost town called Shakespeare. Entering Grant County, the highway continues southeast then northeast after intersecting NM 146. The highway passes over the Continental Divide on the Grant-Luna county line. Continuing east, the highway intersects the city of Deming and the highway becomes concurrent with US 180 as the three highways continue east. The highway enters Doña Ana County as it approaches Las Cruces. US 70 exits the highway as it enters the city, and the Interstate begins to turn south. Just south of the New Mexico State University campus, I-10 has a junction with the southern terminus of I-25. At the I-25 junction, I-10/U.S. Route 180 also becomes concurrent with US 85. At this point, the highway is now headed almost due south before crossing into Anthony, Texas from Anthony, New Mexico.
Note: the speed limit has increased from on I-10 from Mesquite to Anthony at the Texas state line, and I-10 south of Las Cruces is now three lanes in each direction.
History
I-10 replaced US 80 through New Mexico, bypassing major portions of old US 80 in the western portion of the state and in Doña Ana County. US 80 was one of the original United States Numbered Highways established in 1926. The portion of US 80 between the Arizona state line and Anthony was ed on October 6, 1989, while the remainder of the route though the state was removed October 12, 1991. From 1927 to 1960, the section of Interstate 10 between Road Forks and the Arizona state line was designated New Mexico State Road 14. Though it was only long, NM 14 and its Arizona counterpart, SR 86, served as a direct bypass for US 80 between Road Forks and Benson, Arizona. US 80 itself looped south to Douglas, Arizona at the Mexico-US border between Road Forks and Benson. By the late 1940s, NM 14 had been paved and carried the majority of US 80 traffic by 1950. With the advent of I-10, NM 14 was removed from the state road system in 1960. The Interstate was first numbered I-10 by the American Association of State Highway Officials, in cooperation with the Department of Commerce, in 1957.