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Interleukin-27 receptor
The
interleukin-27
receptor
is a
type I cytokine receptor
for interleukin-27. It is a
heterodimer
composed of
the
interleukin 27 receptor, alpha subunit
and
glycoprotein 130
.
IL27RA
essential
for
transcriptional
activation
of
STAT1
and for augmenting the
induction
of
T-bet
expression
during
initiation
of
Th1 cell
differentiation
.