ICAM3
Intercellular adhesion molecule 3 also known as CD50, is a protein that in humans is encoded by the ICAM3 gene.Function
The protein encoded by this gene is a member of the intercellular adhesion molecule family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leukocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.Interactions
ICAM3 has been shown to interact with EZR and Moesin.
