Hugh was the youngest of the three sons of Aimery of Lusignan, Lord of Cyprus, and his first wife, Eschiva of Ibelin. He was born between around 1194/1195 and 1199. Shortly after his birth, he lost his mother. Hugh and his two brothers, Guy and John, were engaged to the three daughters of Isabella I of Jerusalem, as a sign of reconciliation between Cyprus and Jerusalem. Hugh was his father's only son to survive childhood.
Reign
Minority
Hugh was still a minor when his father died on 1 April 1205. The High Court of Cyprus appointed his brother-in-law, Walter of Montbéliard, regent. Walter was also made Hugh's guardian, thus he seized the custody of both the kingdom and the young monarch. Walter intervened in a conflict over the possession of Satalia between the Sultanate of Rum and an adventurer, Aldobrandino, on the latter's behalf, but the Seldjuks captured the town with the assistance of the local Greeks.
Ruler of Cyprus
Hugh reached the age of majorityin September 1210. He called Walter of Montbéliard to account, stating that Walter had kept him in a "state of deprivation" during his minority. He demanded 240,000 white bezants from the ex-regent, claiming that 200,000 bezants had been in the royal treasury when his father died and he had spent 40,000 bezants to secure his own subsistence. Instead of rendering an account, Walter left Cyprus with the assistance of Bohemond IV of Antioch. John of Brienne, the new king of Jerusalem, gave shelter to Walter. In a letter sent to Pope Innocent III, Walter stated that Hugh had expelled him from Cyprus and confiscated his property without the judgement of the High Court. Hugh concluded a treaty with the SeldjuqSultan of Rum which guaranteed that the merchants from Cyprus and Rum could safely run their business in both countries. He gave his sister, Helvis, in marriage to Bohemond IV's rival, Raymond-Roupen, although she had been married to Odo of Dampierre. Odo of Dampierre urged the pope to intervene and prevent the new marriage. Hugh supported John of Brienne's opponents, according to a 1213 letter of Innocent III. The pope also rebuked him for capturing John of Brienne's vassals whom Muslim ships had forced to land at Cyprus. Hugh especially favored the Knights Hospitaller. He exempted them of duties levied on goods bought or sold in Cyprus already at the beginning of his personal rule. He sent reinforcements to them to Syria in 1214. In September 1217, Hugh joined King Andrew II of Hungary on the Fifth Crusade in raiding Muslim lands in Galilee. On his return, he stopped in Tripoli to attend the wedding of his half-sister Melisende on 10 January 1218, but he became ill during the celebration and died. He was buried at the Church of the Hospitallers at Tripoli, then at the Church of the Hospitallers at Nicosia.