Hematologic disease

Myeloid

• Hemoglobinopathies
• *Sickle cell disease
• *Thalassemia
• *Methemoglobinemia
• Anemias
• *Iron-deficiency anemia
• *Megaloblastic anemia
• **Vitamin B₁₂ deficiency
• ***Pernicious anemia
• **Folate deficiency
• *Hemolytic anemias
• **Genetic disorders of RBC membrane
• ***Hereditary spherocytosis
• ***Hereditary elliptocytosis
• ***Congenital dyserythropoietic anemia
• **Genetic disorders of RBC metabolism
• ***Glucose-6-phosphate dehydrogenase deficiency
• ***Pyruvate kinase deficiency
• **Immune mediated hemolytic anemia
• ***Autoimmune hemolytic anemia
• ****Warm antibody autoimmune hemolytic anemia
• *****Idiopathic
• *****Systemic lupus erythematosus
• *****Evans syndrome
• ****Cold autoimmune hemolytic anemia
• *****Cold agglutinin disease
• *****Paroxysmal cold hemoglobinuria
• *****Infectious mononucleosis
• ***Alloimmune hemolytic anemia
• ****Hemolytic disease of the newborn
• *****Rh disease
• *****ABO hemolytic disease of the newborn
• *****Anti-Kell hemolytic disease of the newborn
• *****Rhesus c hemolytic disease of the newborn
• *****Rhesus E hemolytic disease of the newborn
• *****Other blood group incompatibility
• ***Drug induced immune mediated hemolytic anemia
• ****Penicillin
• ****Methyldopa
• **Hemoglobinopathies
• **Paroxysmal nocturnal hemoglobinuria
• **Direct physical damage to RBCs
• ***Microangiopathic hemolytic anemia
• ***Secondary to artificial heart valve
• *Aplastic anemia
• **Fanconi anemia
• **Diamond–Blackfan anemia
• **Acquired pure red cell aplasia
• Decreased numbers of cells
• *Myelodysplastic syndrome
• *Myelofibrosis
• *Neutropenia
• *Agranulocytosis
• *Glanzmann's thrombasthenia
• *Thrombocytopenia
• **Idiopathic thrombocytopenic purpura
• **Thrombotic thrombocytopenic purpura
• **Heparin-induced thrombocytopenia
• Myeloproliferative disorders
• *Polycythemia vera
• *Erythrocytosis
• *Leukocytosis
• *Thrombocytosis
• *Myeloproliferative disorder
• *Transient myeloproliferative disease
• Coagulopathies
• *Thrombocytosis
• *Recurrent thrombosis
• *Disseminated intravascular coagulation
• *Disorders of clotting proteins
• **Hemophilia
• ***Hemophilia A
• ***Hemophilia B
• ***Hemophilia C
• **Von Willebrand disease
• **Disseminated intravascular coagulation
• **Protein S deficiency
• **Antiphospholipid syndrome
• *Disorders of platelets
• **Thrombocytopenia
• **Glanzmann's thrombasthenia
• **Wiskott–Aldrich syndrome

  Hematological malignancies

• Hematological malignancies
• *Lymphomas
• **Hodgkin's disease
• **Non-Hodgkin's lymphoma
• ***Burkitt's lymphoma
• ***Anaplastic large cell lymphoma
• ***Splenic marginal zone lymphoma
• ***Hepatosplenic T-cell lymphoma
• ***Angioimmunoblastic T-cell lymphoma
• *Myelomas
• **Multiple myeloma
• **Waldenström macroglobulinemia
• **Plasmacytoma
• *Leukemias increased WBC
• **Acute lymphocytic leukemia
• **Chronic lymphocytic leukemia
• **Acute myelogenous leukemia
• **Acute megakaryoblastic leukemia, a sub-type of acute myelogenous leukemia
• **Chronic Idiopathic Myelofibrosis
• **Chronic myelogenous leukemia
• **T-cell prolymphocytic leukemia
• **B-cell prolymphocytic leukemia
• **Chronic neutrophilic leukemia
• **Hairy cell leukemia
• **T-cell large granular lymphocyte leukemia
• **Aggressive NK-cell leukemia

  Miscellaneous

• Hemochromatosis
• Asplenia
• Hypersplenism
• *Gaucher's disease
• Monoclonal gammopathy of undetermined significance
• Hemophagocytic lymphohistiocytosis
• Tempi syndrome

  Hematological changes secondary to non-hematological disorders

• Anemia of chronic disease
• Infectious mononucleosis
• AIDS
• Malaria
• Leishmaniasis