HOXB5
Homeobox protein Hox-B5 is a protein that in humans is encoded by the HOXB5 gene.Function
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia and the occurrence of bronchopulmonary sequestration and congenital cystic adenomatoid malformation tissue.
