Growth factor receptor inhibitor
Growth factor receptor inhibitors are drugs that target the growth factor receptors of cells. They interfere with binding of the growth factor to the corresponding growth factor receptors, impeding cell growth and are used medically to treat cancer.
Drugs of this type include those that target the epidermal growth factor receptors of epidermal cells and those that target vascular endothelial growth factor receptors.In cancer treatment, growth factor receptor inhibitors have been used to target cancer cells.
In cancer research, growth factor receptor inhibitors have been applied to protect normal cells selectively from the toxic side-effects of chemotherapy targeted against cancer cells.