Grocott's methenamine silver stain


In pathology, the Grocott-Gomori's methenamine silver stain, abbreviated GMS, is a popular staining method in histology. The stain was originally named after György Gömöri, the Hungarian physician who developed the stain.
It is used widely as a screen for fungal organisms. Particularly useful in staining carbohydrates.
It can be used to identify the yeast-like fungus Pneumocystis jiroveci which causes a form of pneumonia called Pneumocystis pneumonia or pneumocystosis.
The cell walls of these organisms are outlined by the brown to black stain.