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Glutamate-5-semialdehyde
Glutamate-5-semialdehyde
is a
non-proteinogenic amino acid
involved
in the
biosynthesis
of
proline
and
arginine
, as well as in the biosynthesis of
antibiotics
, such as
carbapenems
. It is
synthesized
by the
reduction
of
glutamyl-5-phosphate
by
glutamate-5-semialdehyde dehydrogenase
.