Son of Joyce Nix and George Campbell III, George, at the age of 5 and after his father's imprisonment, developed a close bond with his uncle Ahmad Jackson. Nix is a certified nurse.
In 2012, East Lake improved to 11–2, but again lost in the FHSAA Class 8A region final, this time to Dr. Phillips High School on November 30 by a 31–21 margin. In the first game of the season, when starter Artavis Scott injured his ankle, Campbell stepped in at wide receiver. Later in the season, when the team struggled to get pressure on the quarterback, Campbell moved from safety to defensive end. As a sophomore, his tackle total declined to 56, but his 764 receiving yards earned him 27 major Division I scholarship offers. His offers included Arkansas, Auburn, Boston College, Clemson, Florida, Florida State, Georgia, Georgia Tech, Illinois, Louisville, Miami, Mississippi, Mississippi State, North Carolina State, Notre Dame, Ohio State, South Florida, Tennessee, Texas A&M, UCF, UCLA, Vanderbilt, West Virginia. East Lake junior offensive lineman Mason Cole committed to Michigan's class of 2014 on February 25, which was one day before Cole was invited to participate in the 2014 U.S. Army All-American Bowl. That year Campbell played basketball and ran track for East Lake before having surgery on his left wrist on April 19. The following summer, he ran a 4.36 second 40-yard dash. His 4.36 time was on artificial turf, while he was timed a 4.37 on grass on the same day. He was also measured at in his vertical leap. He was a second team All-Suncoast region and first team All-Pinellas County team selection.
Junior
Prior to his junior season, he verbally committed to the University of Michigan where he would play for Michigan Wolverines football as a freshman for the 2015 team via Twitter. At the time, he still attended East Lake High School, where he was about to play his junior year for the 2013 football team. At the time of his July 27, 2013 verbal commitment, he was ranked as the number one athlete and number three player in the class of 2015 by ESPN. When Scout.com released its first list of 5-star rated football players on August 12, 2013, Campbell was included among the 20 players listed and the only wide receiver included. At the end of that summer prior to his junior year football season, he was one of two juniors selected to the 2013 USA Today preseason All-USA team. He accepted an invitation to participate in the 2015 Under Armour All-America Game in St. Petersburg before the end of October 2013. The November 15 FHSAA Class 7A region quarterfinal that East Lake won 13–12 ended with an alleged punch by a Palmetto High School coach that left Campbell with a cut inside his mouth. Other players were involved in the altercation, which is being investigated by the FHSAA. On November 19, 2013, ESPN moved Campbell up to the number two overall position in the class of 2015. This moved him ahead of Kevin Toliver II, but he remained behind Jashon Cornell. In Campbell's third time in the FHSAA, East Lake finally got past the regional finals, only to lose the following week on December 6, 2013, in the state semifinals in overtime to Dwyer High School 31–24, despite a 65-yard touchdown reception by Campbell. Following the season, Campbell decommitted from Michigan on December 13.
Senior
He subsequently named the 10 schools he was considering, while excluding Michigan on July 28, 2014. The 10 schools were LSU, Alabama, Florida, FSU, Georgia, Clemson, UCLA, Ole Miss, Auburn, and Maryland. On September 5, he selected Florida State.
College
Campbell spent four years at Florida State. His best season was his junior season when he caught 6 passes for 122 yards. Upon graduation, he announced his graduate transfer to Penn State in February 2019. However, he ended up at West Virginia University in June after failing to secure admission into a graduate program at Penn State. 7 of his 19 receptions at West Virginia, where he averaged 24.7 yards per reception, were for touchdowns.
Professional career
After going undrafted in the 2020 NFL Draft, Campbell signed with the New York Jets on May 6, 2020.