GBR-13098


GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor.
Blocking the endogenous striatal dopamine transporter with GBR-13098 in mice has been shown to prevent damage to the DA nerve terminals caused by malonate. It was suggested that DA transporter inhibitors like GBR-13098 could be used to prevent or treat neurodegenerative disorders caused by the effect of mitochondrial dysfunction on DA homeostasis.