Frumka was born in Plotnitsa, a village near Pińsk, during World War I, part of the newly reborn Poland since 1919 after a century of foreign Partitions. She relocated to Warsaw in 1938 to assume a position at the headquarters of the Dror Zionist Youth Movement founded on Polish lands in 1915 in the course of the war with imperial Russia. Following the 1939 invasion of Poland by Nazi Germany and the Soviet Union, Frumka undertook underground activities as leader of the HeHalutz youth movement. Using false identities and facial disguise, she travelled across General Government territory between Jewish ghettos in German-occupied Poland. She witnessed the Holocaust trains departing from train stations to undisclosed death camps during the extermination of the Jews known as the "Final Solution". As a courier, she delivered light weapons procured by the Warsaw Ghetto underground, as well as blueprints, drafted by the headquarters, for the manufacture of Molotov cocktails and hand grenades. Among the Jewish communities she visited, Frumka was referred to as "Die Mameh", Yiddish for "Mom". She relayed the reports of murderous liquidation of so many ghettos that she began to call herself a "gravedigger". block located at the intersection of Niska and Dubois streets in Warsaw commemorating the life and martyrdom of Frumka Płotnicka After the Großaktion Warschau in September 1942 Płotnicka was sent from Warsaw to Będzin in occupied south-western Poland by the Jewish Combat Organization in order to help the self-defence organization there. The seeds of ŻOB were planted in the Warsaw Ghetto only two months earlier, when the German SS headed by Hermann Höfle began the roundups of Jews aimed at deporting 254,000 prisoners to the newly built Treblinka extermination camp. Frumka was the first Jewish courier in the Warsaw Ghetto to smuggle weapons from the Aryan part of the city inside sacks of potatoes. Płotnicka was issued a Paraguayan passport issued by Ładoś Group.
In the Będzin Ghetto the Jewish underground cell was formed already in 1941. The ghetto was never surrounded by a wall, even though it was tightly guarded by the German and the Jewish Ghetto Police. In March 1941 there were 25,171 Jews in Będzin; this increased to 27,000 after the ominous expulsion of the Jewish community of Oświęcim, the location of the Auschwitz II Birkenau redevelopment. In May 1942 deportations to Auschwitz began with the first transport of 3,200 Będzin Jews loaded onto Holocaust trains at the Umschlagplatz. On the advice of Mordechai Anielewicz who stayed in Dąbrowa Basin temporarily in mid-1942, Płotnicka, Brandes and the Kożuch brothers, organized a local chapter of ŻOB. On 3 August 1943, during the final deportation action, the partisans launched an uprising which lasted for several days. Płotnicka was killed in a bunker at Podsiadły Street on the same day. Dedicated to her memory is the engraved Syenitecommemorative plaque, located at the intersection of Niska and Dubois streets in Warsaw. The memorial stone is part of an innercity Memory Trail of the Struggle and Martyrdom of the Jews :pl:Trakt Pamięci Męczeństwa i Walki Żydów w Warszawie|, inaugurated in 1988, extending from the intersection of Zamenhof and Anielewicz streets to the intersection of Dzika and Stawki streets. Płotnicka was registered by Yad Vashem as victim of the Holocaust in 1957.