Born in Guimarães, Meira began his professional career with hometown's Vitória Sport Clube, but only had one solid season with its first team, in 1999–2000, as he appeared in 30 of his 53 games with the Minho side. In 1998 he was also loaned, to F.C. Felgueiras of the second division, being an essential defensive unit as they narrowly missed out on promotion after finishing fifth. In the summer of 2000, Meira joined Primeira Liga giants S.L. Benfica for a €4 million transfer fee plus one player. He played 31 matches in his first season – 30 starts – and was also awarded team captaincy, but the Lisbon club did not win any silverware during his stint.
Stuttgart
In January 2002, Meira signed for VfB Stuttgart in Germany for €7.5 million– it was the Bundesliga club's record transfer fee until July 2007, when they signed Ciprian Marica from FC Shakhtar Donetsk for €8 million, and general managerRolf Rüssmann described the player as a "trophy" signing, showing great ambitions for the future. He made his league debut on the 26th in a 3–0 home win against Hamburger SV, playing the entire game as a stopper. OMeira scored his first goal for Stuttgart on 23 February 2002, in a 1–1 draw at F.C. Hansa Rostock where he also conceded a penalty which resulted in the opponents' goal. His second came on 7 April in a 2–0 away victory over SC Freiburg, and he finished his first year with 14 league appearances to help his side finish in eighth position. In the 2002–03 campaign, Felix Magath fielded Meira in 31 league games, and only a suspension prevented him from taking part in all 34 fixtures as they finished second behind FC Bayern Munich to achieve qualification honours to the UEFA Champions League. He missed two UEFA Cup matches, including the home win against Celtic in the round of 16's second leg, and found the net in the second round's 2–0 home defeat of Ferencvárosi TC. For the 2006–07, Meira was named captain by manager Armin Veh, making him the first Portuguese ever to achieve that feat in the Bundesliga. He appeared in 20 matches and added three goals as the Baden-Württemberg club was crowned national champions for the first in 15 years, adding four in a runner-up run in the DFB-Pokal. Over a six-and-a-half-year spell, Meira made 230 competitive appearances and scored 13 goals. He left the Gottlieb-Daimler-Stadion in summer 2008, aged 30.
Galatasaray
On 20 July 2008, at the end of the 2007–08 season, Stuttgart stripped Meira of the captaincy and announced their intention to sell the player. Two days later, he agreed to a four-year deal at Galatasaray SK for €4.5 million. Meira made his official team debut in the season's Turkish Super Cup, a 2–1 win against Kayserispor, but left Turkey at the end of the campaign, with his team only ranking in fifth position in the Süper Lig.
Zenit
In mid-March 2009, after reported interest from FC Zenit Saint Petersburg as the player grew unsettled in Istanbul, Meira signed for the Russian club for €4.5 million, being awarded the number 3 shirt previously worn by Martin Škrtel. He made his Russian Premier League debut on 15 March 2009, starting in a 1–1 away draw to FC Spartak Moscow. On 5 April he netted his first goal for his new team, in a 3–0 victory at FC Tom Tomsk.
Later years
On 15 August2011, aged 33, Meira joined Real Zaragoza from Spain after mutually terminating his contract with Zenit. He made his official debut 13 days later, starting and being booked in a 0–6 home loss against Real Madrid. In his spell with the Aragonese, Meira featured almost exclusively as a defensive midfielder, partnering Leonardo Ponzio. He terminated his contract on 1 February 2012, as the side were placed last in the league; late into the year, not being able to find a new club, he retired from football.
