Search
Menu
Home
Sources
About
Contacts
FLT4
Fms-related
tyrosine kinase
4
, also known as
FLT4
, is a
protein
which in
humans
is
encoded
by the
FLT4
gene
.
This gene encodes a
tyrosine kinase receptor
for
vascular endothelial growth factors
C
and
D
. The protein is thought to be
involved
in
lymphangiogenesis
and
maintenance
of the
lymphatic endothelium
.
Mutations
in this gene
cause
hereditary lymphedema
type
IA
.
Interactions
FLT4 has been
shown
to
interact
with
SHC1
.