The Ohio Yearly Meeting of the Friends Church was established on October 12, 1812 by the Baltimore Yearly Meeting of the Religious Society of Friends. At the time the Ohio Yearly Meeting included most of the Friends meetings West of the Allegheny Mountains. The first OYM yearly meeting was on August 14, 1813 in Short Creek with Horton Howard presiding. The first Yearly Meeting House was erected in 1814 in Mt. Pleasant, Ohio. Many new local “meeting houses” followed. During the 1800s the Friends movement experienced a separation over theology that would today be characterized as a debate between Unitarian/Universalism and Orthodoxy. Later the Society of Friends again wrestled over traditional Friends practices and Evangelicalism. These separations resulted in multiple groups using the name "Ohio Yearly Meeting". In 1917 the evangelicals moved their headquarters to Damascus, Ohio and became known as the Ohio Yearly Meeting. The Yearly Meeting House in Damascus was used from 1866 until a few years before it was razed in the 1970s. Later, they relocated again, this time to Canton, Ohio. In 1965 the Ohio Yearly Meeting joined the Evangelical Friends Alliance. In 1971 Ohio Yearly Meeting became Evangelical Friends Church - Eastern Region.
By the 1870s, a noted evangelist, David B. Updegraff, supported baptism and communion in Friends churches. His teachings were considered a near-scandal in Friends meetings throughout the world, and resulted in some yearly meetings agreeing to allow for freedom of conscience in those practices. Updegraff largely solidified the EFC-ER's participation in the Evangelical-Holiness camp.
Malone University
The Evangelical Friends Church - Eastern Region was heavily influenced by the leadership of J. Walter and Emma Malone. In 1892, they founded the Cleveland Bible Training Institute — now Malone University in Canton — to train pastors and missionaries. Walter became the first General Superintendent in 1889, although the title was not formalized until 1891. The first missionaries to come out of the school were Esther Baird and Delia Fistler, who served in India. In fact, the school helped to sponsor eight other schools of higher education around the country and around the world.
Twentieth century
Into the twentieth century, EFC-ER expanded its churches, missions, leaders and prominence amongst evangelicals worldwide. Leaders and members of note include Everett L. Cattell, Walter Williams, Cliff Robinson, and Charles DeVol.
Today
The mission of EFC-ER is to equip churches to make disciples.