Rosenberg’s early work in Israel focused on myxobacteriology, hydrocarbon microbiology, surface-active polymers from Acinetobacter, and bioremediation. In collaboration with his department colleagues Eliora Z. Ron and David Gutnik, he introduced the pioneering use of microorganisms and bioemulsifiers to treat oil pollution in oil tankers, pipelines and on beaches In later years he collaborated with Yossi Loya to research coral disease. They demonstrated for the first time that coral bleaching is the result of an infectious disease and that a rise in temperature due to global warming causes pathogenic micro organisms to be more active and cause infectious epidemic diseases. His most recent work has developed the "hologenome concept of evolution". This groundbreaking concept posits that the holobiont and its hologenome, function as a unique biological entity and therefore as a level of selection in evolution. According to the hologenome concept microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment, and the sum of these cooperative interactions characterizes the holobiont as a unique biological entity. He contends that under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are conceived as applied aspects of the hologenome concept.
Awards
In 1983-1984 Rosenberg was appointed as a Fellow of the Guggenheim Foundation. In 1992 he was awarded with the Pan Lab Prize of the Society of Industrial Microbiology and in 1993 he was awarded as a Fogarty International scholar at the National Institute Of Health. Jointly with Prof.Eliora Ron he received the Israel Prize for a Beautiful Israel in 1995. In 2002 he was awarded the Sakov Prize for ecological research and in 2003, the Procter & Gamble Prize of the American Society for Microbiology and together with Yossi Loya, the Landau Prize by Mifaal Hapais in Life Sciences. Rosenberg has supervised numerous graduate students and postdocs. He is a Fellow of the American Academy of Microbiology. He is the author of approximately 270 research papers and reviews, 10 books, and 16 patents.
Selected publications
Books
Rosenberg, E, Zilber-Rosenberg, I.. The Hologenome Concept: Human, Animal and Plant Microbiota. Springer.
Rosenberg, E., E, F, DeLong, S. Lory, E. Stackebrandt, F. Thompson, Eds.. The Prokaryotes.
Rosenberg, E. and U. Gophna, eds.. Beneficial Microorganisms in Multicellular Life Forms Springer, Heidelberg.
Rosenberg, E. and Y. Loya, eds.. Coral Health and Disease Berlin Springer.
Rosenberg, E. and Ron. E. Enhanced bioremediation of oil spills in the sea. Current Opinions in Biotechnology, 27-191-194.
Rosenberg, E.. Microbial diversity as a source of useful biopolymers. J. Ind. Microbiol. 11: 131-137.
Rosenberg, E., J.M. Porter, P.D. Nathan, A. Major and M. Varon. Antibiotic TA: An adherent antibiotic. Bio/Technology 2:796-799.
Rosenberg, M., D.L. Gutnick and E. Rosenberg. Adherence to hydrocarbons: A simple method for measuring cell-surface hydrophobicity. FEMS Microbiol. Lett. 9:29-33 Citation Classic. April 22, 1992.