Hoeppner was born in Tonnin on the island of Wollin in Pomerania on 14 January 1860. The son of a major, he attended the Cadet School in Potsdam from 1872 and in 1879 he was commissioned as a second lieutenant in the 6th Magdeburg Dragoon Regiment. He attended the Prussian Military Academy in 1890. From 1893 to 1899, he was a member of the 14th Dragoon Regiment stationed at Colmar in Alsace, commanding a squadron. Hoeppner married Sophie Eugenie Minette Elisabeth Adele Valentine of Pöppinghausen on 14 July 1885. They had three children: Busso, Margot and Gerd. In 1902 Hoeppner was appointed to the General Staff. He was appointed as a staff officer with the IX Army Corps in Altona in 1904. By 1906 he was a lieutenant colonel and was commander of the 13th Hussars Regiment in Diedenhofen. Two years later he was appointed chief of staff of the VII Army Corps. In September 1912 he was made commander of the 4th Cavalry Brigade in Bromberg and the following year he was raised to the nobility by Kaiser Wilhelm II and granted the nobiliary particlevon before his surname. This was in recognition of his achievements as a staff officer and brigade commander.
World War I
At the start of World War I Hoeppner was Chief of Staff at the 3rd Army headquarters. He remained in this post until spring of 1915 when he took up command of the 14th Reserve Division. Later in 1915 he was appointed Chief of Staff of the 2nd Army and in 1916 he became the commander of the 75th Reserve Division. In October 1916, General Ludendorff decided that the German Air Service needed greater unity of command with a general officer having authority over all the Army's aerial combat and anti-aircraft units both in the field and at home. Ludendorff chose Hoeppner as the new air commander and it was at this time the Air Service was renamed from Fliegertruppe to Luftstreitkräfte. Hoeppner was given the title of Kommandierender General der Luftstreitkräfte, holding the rank of lieutenant-general. He was directly responsible to Hindenburg at Supreme Army Command. Hoeppner reorganized the fragmented air services, greatly increasing the number of Jastas and forming them into Jagdgeschwader. Priority was given to the development of strategies for massed air attacks. In 1917 he was awarded the Pour le Mérite even though as a senior commander he was not directly involved in air combat. The award was resented by some of his junior officers.
Post war
After the war, the German Air Service was dissolved. The German War Ministry issued orders for Von Hoepppner's post to be disestablished on 16 January 1919 although he appears to have continued as Commanding General for a few more days. His final order to his Air Service personnel was issued on 21 January. He then took up command of the 18th Army Corps on 10 April 1919 but resigned from active service at his own request at the end of November 1919. He retired as general of cavalry with permission to wear the uniform of the 13th Hussars Regiment. Hoeppner returned to his estate at Groß-Mokratz on the island of Wollin in the Baltic Sea where he wrote his memoirs. In 1921 he published Deutschlands Krieg in der Luft, a study of the German Air Service from 1914 to 1918. On 26 September 1922 Hoeppner died of Influenza at the age of 62. He was buried in his birthplace, Tonnin, on the island of Wollin.