Genden's expertise is in thyroid, parathyroid surgery, head and neckcancer surgery, and airway reconstruction. Memberships include the New York Head and Neck Society, American Head and Neck Society, American Board of Facial Plastic and Reconstructive Surgery, and the American Broncho-Esophagological Association. In 2006, Genden performed the first jaw transplant using the patient's jaw and bone marrow. Genden has authored six textbooks on oncology and microvascular head and neck reconstruction. He published more than 200 peer-reviewed articles and co-authored a chapter about facial transplantation in for Facial Plastic Surgery Clinics of North America. He served as a co-investigator on more than 15 clinical trials. He received in 1983 the Brooks School and received the Distinguished Brooksian Recipient Award in 2018, and is a contributing editor at the Journal of the American Medical Association's JAMAevidence.
Oral squamous cell carcinoma: histologic risk assessment, but not margin status, is strongly predictive of local diseasefree and overall survival. Brandwein-Gensler M, Teixeira MS, Lewis CM, Lee B, Rolnitzky L, Hille JJ, Genden E, Urken ML, Wang BY. Am J Surg Pathol 2005
Treatment considerations for head and neck cancer in the elderly. Genden EM, Rinaldo A, Shaha AR, Clayman GL, Werner JA, Suarez C, Ferlito A. J Laryngol Otol, 2005
Reepithelialized orthotopic tracheal allografts expand memory cytotoxic T lymphocytes but show no evidence of chronic rejection. Cleven HA, Genden EM, Moran TM. Transplantation, 2005
Is there a role for selective neck dissection after chemoradiation for head and neck cancer? Robbins KT, Ferlito A, Suarez C, Brizel DM, Bradley PJ, Pellitteri PK, Clayman GL, Kowalski LP, Genden EM, Rinaldo A. J Am Coll Surg, 2004
Pharyngocutaneous fistula following laryngectomy. Genden EM, Rinaldo A, Shaha AR, Bradley PJ, Rhys-Evans PH, Ferlito A. Acta Otolaryngol, 2004
Complications of free flap transfers for head and neck reconstruction following cancer resection. Genden EM, Rinaldo A, Suarez C, Wei WI, Bradley PJ, Ferlito A. Oral Oncol, 2004
Effect of fibrin matrix and vascular endothelial growth factor on reepithelialization of orthotopic murine tracheal transplants. Govindaraj S, Gordon R, Genden EM. Ann Otol Rhinol Laryngol, 2004
Reconstruction of the hard palate with the radial forearm free flap: Outcomes and Quality of Life. Wallace D, Genden EM, Urken ML. Head and Neck, 2004
Sensory topography of the oral cavity and the impact of free flap reconstruction: A preliminary study. Zur KB, Genden EM, Urken ML. Head and Neck, 2004
Prediction of Postoperative Hypocalcemia after Thyroid Surgery using a Rapid Intraoperative Parathyroid Hormone Assay. Mandell DL, Genden EM, Mechanick JI, Bergman DA, Urken ML. Arch Otolaryngol Head Neck Surg, 2004