Pease was born on 31 May 1767 as the eldest son of the Darlington woollen manufacturer Joseph Pease and his wife, Mary Richardson. The family were prominent Quakers: his brother Joseph Pease was a founder of the Peace Society in 1817 and involved in the second, 1839 Anti-Slavery Society, for which he wrote tracts. Edward boarded at a school in Leeds run by Joseph Tatham the elder, and then joined his father's woollen business at the age of 15. On 30 November 1796, he married a fellow Quaker, Rachel, daughter of John Whitwell, of Kendal. They had five sons and three daughters.
Railway promotion
In 1809, Pease became involved in longstanding aspirations to improve navigability on the lower Tees, so that County Durham collieries could compete more effectively with those of Tyneside to supply coal to London. This was abandoned in favour of a railway. Meanwhile, Pease introduced into the scheme the steam engine maker George Stephenson, and an initial act of Parliament for a horse-drawn railway was immediately superseded by one for a steam-hauled line. Also prominent was a cousin of his, the Darlington banker Jonathan Backhouse, and in promoting steam, Nicholas Wood, the engineer and manager of Killingworth Colliery. Pease, described at the time as "a man of weight, of prudence, of keen commercial instincts", was charged with showing that steam would be a sound investment, and his young son Joseph drew up the company prospectus. The scheme was approved by Parliament in 1821. Robert Stephenson and Company was founded in Newcastle in 1823 to manufacture locomotives, with Pease as one of the principals. Stephenson was put in charge of the project and the line opened on 27 September 1825. The company initially provided only the track, which was hired out to whoever wished to run a train hauled either by horses or by steam. The transition to standard railway management was gradual, spurred on by frequent disputes between drivers about right of way and by the dangers of the higher speeds of steam locomotives.
"Perseverance"
In 1829 Pease retired from the railway, whose running was taken over by his second son Joseph Pease. Joseph, like his uncle and namesake, was prominent in the anti-slavery movement and in prison reform. In 1832 he became the first Quaker to sit in Parliament. Edward Pease had extensive connections among the Quaker banking community, which helped considerably in promoting the railway. He also invested strongly in 1823 in Stephenson's new company for building locomotives in Newcastle upon Tyne. He retired from business in 1833, but not from religious life as a Quaker. Edward had cordial relations with Stephenson and his son Robert for the rest of his life. He died of heart failure in Darlington on 31 July 1858 and was buried in the Quaker burial-ground in Skinnergate. Samuel Smiles described Pease as "a thoughtful and sagacious man, ready in resources, possessed of indomitable energy and perseverance." An edition of his diaries appeared in 1907. There is a statue of Joseph Pease in the centre of Darlington. Locomotion No 1, the first engine to haul passengers by steam on a public railway, still stands in Darlington as a monument to Edward Pease and the Stockton and Darlington Railway. On the day the foundation stone was being laid for the pedestal on which to display it, Henry Pease concluded his speech by saying ''"he rejoiced at seeing the first locomotive about to be placed in a suitable position, so as to hand down to posterity a memorial of one of the greatest events the civilised world ever witnessed."