Meads was raised in Oxford, Michigan. His father, Dr. George Edgar Meads, Sr., was a dentist and an alumnus of the University of Michigan. Meads was a star athlete at Oxford High School, receiving a total of 12 varsity letters in football, basketball, baseball, and track. He earned all-state honors in the half-mile.
Michigan
Meads received a University of Michigan Regent's Scholarship, an academic award, to attend the University of Michigan. He enrolled in 1952 and played for the school's all-freshman football team. As a sophomore, he was a backup for the 1953 team. As a junior, Meads started all nine games at right guard for the 1954 Michigan Wolverines football team. That team compiled a 6-3 record and was ranked No. 15 in the final AP and UPI polls. On October 16, 1954, made the key play in Michigan's 7-0 victory over Northwestern. After a Northwestern fumble, Meads recovered the ball at the Northwestern 24-yard line. Meads' recover set up the only touchdown of the game. As a senior, Meads was chosen as the captain of the 1955 Michigan Wolverines football team. He later recalled, "And when I became a captain as a senior, it surpassed my wildest expectations and dreams." Meads started all nine games at right guard, and the team finished the season with a 7-2 record and ranked No. 12 and No. 11 in the final AP and UPI polls. Meads was selected to play in the Senior Bowl in Mobile, Alabama on January 7, 1956. While attending Michigan, Meads was also a member of the Sphnix and Michigamua honor societies. He graduate from Michigan in 1956.
Western Ontario
After graduating from Michigan, Meads enrolled in medical school at the University of Western Ontario. He played football at the center position for the UWO football team in 1957. At the conclusion of the season, Meads was selected by the Canadian Press, coaches, and sports writers as a first-team player on the Senior Intercollegiate Football Union 1957 all-star team. He also helped lead the Western Ontario Mustangs to the 1957 Canadian national football championship and was named the 1957 most valuable player. Meads played for UWO again in 1958, but suffered a concussion. UWO's head coachJohn Metras refused to let Meads remain on the team out of concern that Meads could suffer a further injury. Meads later spoke about Metras: "He was a very caring and sensitive coach whose exterior belied the interior feeling and warmth he had for his players."
Later years
Meads became a doctor in the 1960s. In the late 1960s, he joined the United States Army Medical Corps. Serving with the rank of Major, he was chief of surgery at field hospitals during the Vietnam War. He received a Bronze Star Medal in 1969. After his discharge from the U.S. military, Meads settled in London, Ontario. He was the chief of surgery at St. Joseph Hospital from 1980 to 1990. He was also a professor of surgery at UWO for 34 years. In 2010, Meads became one of the inaugural inductees into the Oxford Athletic Hall of Fame. He has also been inducted into the UWO Athletics Hall of Fame.