Manion attended Berklee College of Music after graduating from Lakewood High School in 1970 and as a youth played in several bar bands on the Jersey Shore. These included Lazarus who recorded an album in Nashville on the Shelby Singleton Label in 1970, The Dark Side and Little Joe and the Kokomo's. It was while playing with these bands along with his late night jamming at the infamous Upstage Club in the late sixties that he first met Southside Johnny, and Bruce Springsteen.
Southside Johnny and the Asbury Jukes
In 1976, together with trumpet player Tony Palligrosi, he auditioned and joined the Asbury Jukes. He subsequently became a permanent member of the band's horn section – The Miami Horns. He is featured prominently on the album Hearts Of Stone, playing a baritone sax solo on the track "I Played The Fool". In the early 1980s, Manion was also featured on Van Zandt's solo album, Men Without Women, released under the name Little Steven & The Disciples Of Soul. He provided another baritone sax solo on the track "Forever".
On 2/1/09 Manion performed and played baritone sax as part of a 5 piece horn section with Bruce Springsteen and the E Street Band during the halftime show at Super Bowl XLIII in Tampa, Florida. He has also toured and recorded intermittently with Bruce Springsteen and the E Street Band. He first toured with Springsteen in August 1976 during the Born to Run tour. During the Born in the U.S.A. Tour, together with The Miami Horns, Richie "La Bamba" Rosenberg, Mark Pender, Mike Spengler and Stan Harrison, Manion also made several guest appearances, most notably at Meadowlands Arena in August 1984; a version of "Tenth Avenue Freeze-Out" from that date is included on the Live/1975-85 album. The subsequent Tunnel of Love Express Tour of 1988, did however feature a horn section much more prominently. Manion together with Rosenberg, Pender, Spengler and Mario Cruz, sometimes referred to as The Tunnel Of Love Horns, accompanied Springsteen throughout the tour. They also made occasional guest appearances during the Human Rights Now! Tour. From 2012-2014, Manion was part of the E Street Horns appearing on the Wrecking Ball World Tour and High Hopes Tour.
Robert Cray
Between 1991 and 1994, Manion was also a full-time member of The Robert Cray Band and played alongside B.B. King, Albert Collins and John Lee Hooker. Together with trumpet player Mark Pender, they played and arranged horns on the Grammy-nominated Cray album, Shame + A Sin.