ERAP2


Endoplasmic reticulum aminopeptidase 2 is a protein that in humans is encoded by the ERAP2 gene.

Function

hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex class I molecules rely on aminopeptidases such as ERAP1 and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum following cleavage in the cytoplasm by tripeptidyl peptidase II.