Dimethylaminophosphorus dichloride
Dimethylaminophosphorus dichloride is an organophosphorus compound with the formula Me2NPCl2. A colorless liquid, it is a reagent in the preparation of other organophosphorus compounds. Many analogous compounds can be prepared from the reactions of secondary amines and phosphorus trichloride:Reactions
Further equivalents of amine react with dialkylaminophosphorus dichlorides:
Since the P-NR2 bond is not attacked by Grignard reagents, dimethylaminophosphorus dichloride can be selectively dimethylated:
The resulting dimethylphosphino derivative, a structural relative of tetramethylhydrazine, reacts with hydrogen chloride to give chlorodimethylphosphine:
