Deoxycytidine
Deoxycytidine is a deoxyribonucleoside, a component of deoxyribonucleic acid. It is similar to the ribonucleoside cytidine, but with one hydroxyl group removed from the 2' position.
Can be phosphorylated at C-5 by Deoxycytidine kinase converting it to a thiamine nucleotide, a DNA precursor.
It can also be used as a precursor for a treatment for MDS patients. This compound can slows the cell cycle by interfering with the methylation of the P15/INK4B gene, increasing the expression P15/INK4B protein. which subdues the transformation of MDS to leukemia.
