Cliff spent the first seven years of his career working as an academic, initially at the University of Sussex UK and then as an associate professor in the MIT Computer Science and Artificial Intelligence Laboratory, Cambridge USA. Cliff's early research was in computational neuroscience/neuroethology studying visual control of gaze and flight in airborne insects; in using artificial evolution to automate the design of autonomous mobile robots; and in studying the coadaptive dynamics of competitive co-evolutionary arms-races. In 1996, while working as a consultant for Hewlett Packard Labs, Cliff invented the "ZIP" trading algorithm. In 1998 he resigned his post at MIT to take up a job as a senior research scientist at the HP Labs European Research Centre in Bristol, UK, where he founded and led HP's Complex Adaptive Systemsresearch group. In early 2005, Cliff moved to Deutsche Bank's Foreign Exchange trading floor in London, where he worked as a director in Deutsche's FX Complex Risk Group. In late 2005, Cliff resigned from Deutsche to serve as a Professor of Computer Science at the University of Southampton. In October 2005 Cliff was appointed Director of a UK national research consortium, addressing issues in the science and engineering of Large-scale Complex IT Systems : this £14m research project involved approximately 250 person-years of effort over the years 2007-2014. In July 2007, Cliff moved to become Professor of Computer Science at the University of Bristol. The LSCITS Initiative shared much with the research effort in the USA directed at Ultra-Large-Scale Systems. In 2011, Cliff and Linda Northrop jointly authored a paper on the global financial markets as ultra-large-scale systems, commissioned by the UK Government Office for Science. From 2010-2012 Cliff was a member of the 8-person core Lead Expert Group which led the UK Government's Government Office for Science two-year investigation into The Future of Computer Trading in Financial Markets. In addition to Cliff, the other members of the LEG were Philip Bond, Clara Furse, Charles Goodhart, Andy Haldane, Kevin Houstoun, Oliver Linton, and Jean-Pierre Zigrand, co-Director of the Systemic Risk Centre. The investigation commissioned large volumes of peer-reviewed research from international experts, all of which was published by the Government Office for Science and which is summarised in the project's extensive final report. Cliff is a regular presenter on the stage-show GCSE Science Live where large audiences of schoolchildren in years 10-11 watch presentations from well-known scientists. Other scientists involved in GCSE Science Live shows include Maggie Aderin-Pocock, Jim Al-Khalili, Richard Dawkins, Ben Goldacre, Steve Jones, Sir David King, Simon Singh and Lord Winston. In December 2013 Cliff presented a one-off TV documentary on BBC Four titled The Joy of Logic. The programme explored the human quest for certainty and sound reasoning, and the development of logical machines and computers. In April 2015 The Joy of Logic won the top prize - Best International Film - at Europe's leading Science Film Festival, Academia Film Olomouc. It had previously been nominated for international documentary film/TV awards including a "Rockie" at the Banff World Media Festival and a Grierson Award in the UK.