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Daf-7
The
DAF-7
gene
encodes for the
ortholog
of
GDF11
, a
ligand
of
TGF-beta signaling pathway
, in the
worm
Caenorhabditis
elegans
. When
binds
to the
complex
of
type II
receptor
Daf-4
and
type I
receptor
Daf-1
, this
receptor protein serine/threonine kinase
will
phosphorylation
activate
the
Smad Protein
Daf-8/14.